Glucosamine

Intervention2 papers5 findingsPubChem 439213ChEBI 47977

Outcomes

1

Colorectal cancer mortality

no changein humans1RR 0.99Low certainty

1 study
  1. Glucosamine has no effect on colorectal cancer mortality in humans (pooled RR 0.99, 95% CI 0.57 to 1.71).

    Humans

    Glucosamine Use and Its Association with Colorectal Cancer and Mortality: A Systematic Review and Meta-Analysis · Journal of Cancer · 11 Aug 2026

Associations

4

Cancer mortality

downin humans1HR 0.94Low certainty

1 study
  1. Glucosamine is associated with cancer mortality in humans (pooled HR 0.94, 95% CI 0.91 to 0.98).

    Humans

    Glucosamine Use and Its Association with Colorectal Cancer and Mortality: A Systematic Review and Meta-Analysis · Journal of Cancer · 11 Aug 2026

Cardiovascular mortality

downin humans1HR 0.82Low certainty

1 study
  1. Glucosamine is associated with cardiovascular mortality in humans (pooled HR 0.82, 95% CI 0.75 to 0.89).

    Humans

    Glucosamine Use and Its Association with Colorectal Cancer and Mortality: A Systematic Review and Meta-Analysis · Journal of Cancer · 11 Aug 2026

Mortality

downin humans1HR 0.84Low certainty

1 study
  1. Glucosamine is associated with mortality in humans (pooled HR 0.84, 95% CI 0.76 to 0.94).

    Humans

    Glucosamine Use and Its Association with Colorectal Cancer and Mortality: A Systematic Review and Meta-Analysis · Journal of Cancer · 11 Aug 2026

Colorectal cancer

downin humans1HR 0.87Low certainty

1 study
  1. Glucosamine lowers the risk of colorectal cancer in humans (pooled HR 0.87, 95% CI 0.82 to 0.92).

    Humans

    Glucosamine Use and Its Association with Colorectal Cancer and Mortality: A Systematic Review and Meta-Analysis · Journal of Cancer · 11 Aug 2026

Colorectal cancer →

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