FNDC5
Gene3 papers2 findingsHGNC 20240MGI 1917614NCBI Gene 252995Taxon 9606
- Animals2
Interventions
2Exercise
upin mice1
1 study
Exercise
upin mice1
Exercise increases FNDC5 in mice.
Animalsin doxorubicin-treated miceheart
Exercise protects mouse hearts from chemotherapy toxicity by suppressing cellular senescence · Research Square · 29 Sep 2026 · Preprint
High-intensity interval training
upin rats1
1 study
High-intensity interval training
upin rats1
High-intensity interval training increases FNDC5 in rats.
“However, FNDC5 protein expression was increased in trained groups.”
Animalshippocampus8-week
High-intensity interval training modulates APP expression and reduces neuronal apoptosis in a β-amyloid-induced model of Alzheimer's disease: hippocampal evidence · Experimental brain research · 25 Sep 2026
Latest
3Exercise protects mouse hearts from chemotherapy toxicity by suppressing cellular senescence
Physical activity preserved cardiac function and sustained FNDC5 and irisin signaling in mice exposed to doxorubicin.Physical activity preserved cardiac function and sustained FNDC5 and irisin signaling in mice exposed to doxorubicin.