Moderate-intensity aerobic exercise

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab

Animals1

Outcomes

COL1A1

upin mice1

1 study

Moderate-intensity aerobic exercise increases COL1A1 in mice.
“the protein and mRNA expression levels of COL I, COL II and COL III were significantly higher than those in the control group and the high-intensity group.”
Animalsaging miceskeletal muscle8 weeksmalesn = 6
Moderate-intensity aerobic exercise improves skeletal muscle function in aging mice by promoting collagen fiber proliferation
Practical Geriatrics20 Sep 2026

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