Irisin

Intervention1 paper1 findingPubChem 5281777ChEBI 5963

Animals1

Outcomes

Cellular senescence

downin human cells1

1 study

Irisin decreases cellular senescence in human cells.
Cellsin doxorubicin-treated human cardiomyocytes and endothelial cells
Exercise protects mouse hearts from chemotherapy toxicity by suppressing cellular senescence · Research Square · 29 Sep 2026 · Preprint

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Latest

Research SquareAnimalsPreprint30 Sep

Exercise protects mouse hearts from chemotherapy toxicity by suppressing cellular senescence

Physical activity preserved cardiac function and sustained FNDC5 and irisin signaling in mice exposed to doxorubicin.Physical activity preserved cardiac function and sustained FNDC5 and irisin signaling in mice exposed to doxorubicin.

Experimental PhysiologyReview29 Sep

Musculoskeletal decay and bone-muscle crosstalk during physical disuse: Mechanisms and integrated countermeasures

MedicinaHumans28 Sep

Fall-Related Physical Function, Executive Function, and Myokine Responses in Older Women with Obesity Participating in a 16-Week Combined Aquatic Exercise Program: A Prospective Observational Study