NLRP3 inflammasome

Papers on NLRP3 inflammasome

541 papers40 new in 30 days

Saturday, October 24

Cell

Raising taurine improves health during aging in mice

Experiments in aged mice found better health span and fewer deaths from sepsis and inflammation after researchers raised taurine levels.Experiments in aged mice found better health span and fewer deaths from sepsis and inflammation after researchers raised taurine levels.

Figure from Cell
Mouse studyTaurine

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Research Square

Gut microbes from hearing loss patients trigger inner ear damage in young mice

Fecal transplants from elderly hearing loss patients induced blood-labyrinth barrier breakdown, neuroinflammation, and hair cell loss in recipient mice.Fecal transplants from elderly hearing loss patients induced blood-labyrinth barrier breakdown, neuroinflammation, and hair cell loss in recipient mice.

Study design. A.B: Two-sample MR analysis were performed to quantify the causal relationship between gut microbiota and ARHL.
Preprint: experiments in miceEar

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Research Square

Compound reduced disease-linked aging-like gene changes in mice

In mice with chemically induced Gaucher disease, MA-5 reduced aging-like gene changes, with particularly prominent effects in brain immune cells.In mice with chemically induced Gaucher disease, MA-5 reduced aging-like gene changes, with particularly prominent effects in brain immune cells.

MA-5 ameliorates disease phenotypes and neuroinflammation in GD mice.
Preprint: mouse studyInterventions

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