NLRP3
Biomarker1 paper
- Animals1
Latest
12The immunoproteasome in Alzheimer's disease: a dual regulator of tau pathology and microglial senescence
Cathelicidin peptide aids fracture healing in young mice but impairs it in aged mice
Depleting Camp accelerated bone callus formation in aged mice while delaying repair in young mice through P2X7 receptor and NLRP3 signaling.Depleting Camp accelerated bone callus formation in aged mice while delaying repair in young mice through P2X7 receptor and NLRP3 signaling.
Gut microbes from hearing loss patients trigger inner ear damage in young mice
Fecal transplants from elderly hearing loss patients induced blood-labyrinth barrier breakdown, neuroinflammation, and hair cell loss in recipient…Fecal transplants from elderly hearing loss patients induced blood-labyrinth barrier breakdown, neuroinflammation, and hair cell loss in recipient mice.
An Update of Oxidative Stress in Atherosclerosis with Emphasis on the LOX-1-NLRP3 Inflammasome Axis
Dual cognitive and motor training improves cognitive function in aging rats
The combined regimen lowered TMAO accumulation and suppressed inflammatory signaling more effectively than cognitive training alone.The combined regimen lowered TMAO accumulation and suppressed inflammatory signaling more effectively than cognitive training alone.
NLRP3 inflammasome activity shifts toward regulating cell fate in aged macrophages
Inhibiting the NLRP3 inflammasome with MCC950 reduced apoptosis but increased senescence in aged bone marrow-derived macrophages.Inhibiting the NLRP3 inflammasome with MCC950 reduced apoptosis but increased senescence in aged bone marrow-derived macrophages.