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Body system17 papersUBERON 0001690
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17Auditory nerve myelin degeneration defines a subtype of age-related hearing loss
Researchers linked poor auditory nerve synchrony and myelin degradation to amplified communication difficulties in older humans, beyond standard…Researchers linked poor auditory nerve synchrony and myelin degradation to amplified communication difficulties in older humans, beyond standard hearing thresholds.
Short-Term Audiometric Trajectories in Older Adults Receiving Systemic Human Umbilical Cord-Derived Mesenchymal Stem Cells: An Exploratory Single-Arm Substudy
Rapid auditory readout tracks nerve loss in gerbils
A machine-learning model trained on gerbil synapse counts separated age groups above chance when tested on 56 human listeners.A machine-learning model trained on gerbil synapse counts separated age groups above chance when tested on 56 human listeners.
Gut microbes from hearing loss patients trigger inner ear damage in young mice
Fecal transplants from elderly hearing loss patients induced blood-labyrinth barrier breakdown, neuroinflammation, and hair cell loss in recipient…Fecal transplants from elderly hearing loss patients induced blood-labyrinth barrier breakdown, neuroinflammation, and hair cell loss in recipient mice.
Association between presbycusis and cognitive function: contributing factors in older adult
IGF-1 and SLC25A33 preserve cochlear blood barrier integrity in aged mice
Targeting this pathway curbs mitochondrial oxidative stress and pericyte activation to partially restore auditory function in mouse models.Targeting this pathway curbs mitochondrial oxidative stress and pericyte activation to partially restore auditory function in mouse models.
Hearing Loss Prevalence Among Older US Adults: HRS 2016 to 2018 Hearing Screener Data
Hearing aids did not cut dementia conversion in older adults
Over 24 months, dementia conversion was 3.09% with hearing aids compared with 4.74% with hearing care education, a non-significant difference.Over 24 months, dementia conversion was 3.09% with hearing aids compared with 4.74% with hearing care education, a non-significant difference.
Sensory brain responses rise with age as cognitive ones decline
In 40 older and 37 younger adults tested with magnetoencephalography, aging amplified early sensory deviance responses but attenuated later cognitive…In 40 older and 37 younger adults tested with magnetoencephalography, aging amplified early sensory deviance responses but attenuated later cognitive network activity.
Auditory brainstem signals track age-related hearing deficits
In normal-hearing listeners, auditory brainstem responses and behavioral detection thresholds revealed that declining Wave V amplitudes correlated…In normal-hearing listeners, auditory brainstem responses and behavioral detection thresholds revealed that declining Wave V amplitudes correlated with poorer temporal processing at higher sound levels.