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atp12

There is 1 paper on atp12 in aging research: none in people yet, 1 in cells. The newest story, Nov 3, 2026: “Loss of Atp12 protein shortens lifespan in fission yeast”.

Gene

1 paper studies it4 findings

NCBI GeneTaxon

1 new paper in 30 daysSee all 1

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Cells1

Effects

4

FZO1 protein stability

upin fission yeast cells1

1 study

  1. atp12 increases fzo1 protein stability in fission yeast cells.

    “Atp12 physically interacts with Fzo1 and stabilizes its protein levels.”

    Cells

    Loss of Atp12 protein shortens lifespan in fission yeast

    Microbiology spectrum

Mitochondrial function

upin fission yeast cells1

1 study

  1. atp12 improves mitochondrial function in fission yeast cells (shown by atp12 deletion).

    “its deletion leads to severe mitochondrial fragmentation, reduced complex II activity, dissipation of mitochondrial membrane potential, and a marked shortening of CLS.”

    Cellsshown by atp12 deletion

    Loss of Atp12 protein shortens lifespan in fission yeast

    Microbiology spectrum

Mitochondrial fragmentation

downin fission yeast cells1

1 study

  1. atp12 decreases mitochondrial fragmentation in fission yeast cells (shown by atp12 deletion).

    “its deletion leads to severe mitochondrial fragmentation, reduced complex II activity, dissipation of mitochondrial membrane potential, and a marked shortening of CLS.”

    Cellsshown by atp12 deletion

    Loss of Atp12 protein shortens lifespan in fission yeast

    Microbiology spectrum

Chronological lifespan

upin fission yeast cells1

1 study

  1. atp12 extends chronological lifespan in fission yeast cells (shown by atp12 deletion).

    “its deletion leads to severe mitochondrial fragmentation, reduced complex II activity, dissipation of mitochondrial membrane potential, and a marked shortening of CLS.”

    Cellsshown by atp12 deletion

    Loss of Atp12 protein shortens lifespan in fission yeast

    Microbiology spectrum

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 11 paper in 12 months
Microbiology Spectrum

Loss of Atp12 protein shortens lifespan in fission yeast

Experiments in fission yeast showed that the protein stabilizes machinery that joins mitochondria, the cells’ energy-producing structures, together.Experiments in fission yeast showed that the protein stabilizes machinery that joins mitochondria, the cells’ energy-producing structures, together.

Cell studyMechanisms
Paper

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