MitochondriaReview
Mitochondrial Quality Control Links Exercise to Sterile Inflammation in the Cardiovascular System: A Narrative Review
Abstract · CC BY
Preservation of mitochondrial integrity has emerged as a central hub in the anti-inflammatory effect of exercise. This narrative review advances a framework in which mitochondrial damage-associated molecular patterns (mtDAMPs) serve as the mechanistic bridge between exercise and inflammation.
- Chronic inflammation
- Disabled macroautophagy
- Mitochondrial dysfunction
- AMPK signalling
- Mitochondrial biogenesis (PGC-1α)
- Mitophagy
- NF-κB signalling
- NLRP3 inflammasome
- Oxidative stress and ROS signalling
- cGAS–STING signalling
- AIM2
- CGAS
The paper
Mitochondrial Quality Control Links Exercise to Sterile Inflammation in the Cardiovascular System: A Narrative Review
Wen Y, Zhang P, Liao X et al.
Antioxidants · 7 Sep 2026