Loss of chromosome Y
Biomarker1 paper3 findings
Effects
1Cardiac fibrosis
upin mice1
1 study
Cardiac fibrosis
upin mice1
Loss of chromosome Y induces cardiac fibrosis in mice.
Reviewhematopoietic systemmales
Mosaic Loss of Chromosome Y (LOY): From Genomic Instability to Disease and Single-Cell Detection · Frontiers in bioscience (Landmark edition) · 1 Sep 2026
Associations
2Cardiovascular disease
upin humans1
1 study
Cardiovascular disease
upin humans1
Loss of chromosome Y is associated with cardiovascular disease in humans.
Reviewbloodmales
Mosaic Loss of Chromosome Y (LOY): From Genomic Instability to Disease and Single-Cell Detection · Frontiers in bioscience (Landmark edition) · 1 Sep 2026
Lifespan
downin humans1
1 study
Lifespan
downin humans1
Loss of chromosome Y is associated with lifespan in humans.
Reviewbloodmales
Mosaic Loss of Chromosome Y (LOY): From Genomic Instability to Disease and Single-Cell Detection · Frontiers in bioscience (Landmark edition) · 1 Sep 2026