Eye
Body system45 papersUBERON 0000970
- Humans29
- Animals8
- In silico4
Latest
45Identifying Patients with Rapid Progression to Diabetic Retinopathy in Type 2 Diabetes: A Simple Prediction Model for Community Settings
Retinal age gap in unilateral retinal diseases with unaffected fellow eye: phakia and vascular pathology impact retinal age prediction
Disentangling and Fusing Neurostructural and Vascular Ageing for Retinal Age Prediction
Retinal vascular changes track mortality risk in humans
Increased retinal fractal dimension carried a mortality hazard ratio of 0.92 per standard deviation, whereas arteriolar widening carried a hazard…Increased retinal fractal dimension carried a mortality hazard ratio of 0.92 per standard deviation, whereas arteriolar widening carried a hazard ratio of 1.09.
Retinal vessel traits associate with balance impairment
Greater venular width tracked higher odds of balance impairment (OR, 1.61), while greater arteriolar area tracked lower odds (OR, 0.82) over three…Greater venular width tracked higher odds of balance impairment (OR, 1.61), while greater arteriolar area tracked lower odds (OR, 0.82) over three years.
Membrane attack complex deposits on pericytes in human eyes
Single-cell analysis of four aged human donor eyes revealed complement membrane attack complexes concentrated primarily on pericytes, smooth muscle…Single-cell analysis of four aged human donor eyes revealed complement membrane attack complexes concentrated primarily on pericytes, smooth muscle cells, and macrophages.
Loss of MYO1C causes age-dependent rod dysfunction in mice
Global and rod-specific knockout mice developed rhodopsin mislocalization and progressive scotopic vision loss starting at six months of age.Global and rod-specific knockout mice developed rhodopsin mislocalization and progressive scotopic vision loss starting at six months of age.
Macrophage-derived VEGFA maintains eye outflow in mice
Deleting Vegfa in CX3CR1-positive macrophages raised intraocular pressure and reduced aqueous humor outflow facility in nine-month-old mice.Deleting Vegfa in CX3CR1-positive macrophages raised intraocular pressure and reduced aqueous humor outflow facility in nine-month-old mice.
Long read sequencing of retinal RNA improves killifish transcriptome annotation
Engineered cardiac transcription factor restores vision and reduces frailty in aging mice
A genome-scale screen in retinal cells identified NKX2-5 variants that conferred oxidative resilience and improved physical function without…A genome-scale screen in retinal cells identified NKX2-5 variants that conferred oxidative resilience and improved physical function without detectable toxicity.
Age-Related Changes in Differential Corneal Thickness and Their Correlation with With-the-Rule and Against-the-Rule Corneal Astigmatism
Severe vision impairment is associated with cumulative social risk among adults in Puerto Rico: a population-based study
PFOS exposure is linked to higher glaucoma risk in humans
An analysis of NHANES participants from 2005 to 2008 and Mendelian randomization linked PFOS exposure to higher glaucoma risk.An analysis of NHANES participants from 2005 to 2008 and Mendelian randomization linked PFOS exposure to higher glaucoma risk.
Childhood famine exposure tied to multimorbidity in older adults
In older Chinese adults, preschool famine exposure increased cardiometabolic multimorbidity risk (OR: 2.03), and school-age exposure raised complex…In older Chinese adults, preschool famine exposure increased cardiometabolic multimorbidity risk (OR: 2.03), and school-age exposure raised complex multimorbidity risk (OR: 2.27) versus nonexposed controls.