Mosaic loss of chromosome X

Biomarker2 papers1 finding

  • Humans1

Effects

1

Disease incidence

no changein humans1

1 study
  1. Mosaic loss of chromosome X has no effect on disease incidence in humans.

    Humansn = 450,587

    Age-related clonal hematopoiesis and mosaic sex chromosome loss define distinct systemic proteomic programs and disease vulnerabilities · medRxiv · 31 Aug 2026 · Preprint

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medRxivHumansPreprint

Clonal hematopoiesis is linked to frailty in human cohorts

An analysis of 730,088 participants across four cohorts found clonal hematopoiesis was strongly associated with incident frailty and faster functional…An analysis of 730,088 participants across four cohorts found clonal hematopoiesis was strongly associated with incident frailty and faster functional decline.