Cancer/testis antigen expression

Biomarker

1 paper1 finding

Humans1

Upstream

Loss of chromosome Y

upin silico1

1 study

Loss of chromosome Y increases cancer/testis antigen expression in silico.
“In some entities, but not in ccRCC, cancer/testis antigen expression was higher in LOY tumors.”
In silicoin some cancer entities, but not in ccRCCmales
Loss of the Y chromosome barely alters tumour gene activity
bioRxiv9 Oct 2026Preprint

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bioRxiv9 Oct

Loss of the Y chromosome barely alters tumour gene activity

Analyses of human kidney tumours, mice and cell lines showed that losing the Y chromosome produces few broad changes in gene activity across cancers.Analyses of human kidney tumours, mice and cell lines showed that losing the Y chromosome produces few broad changes in gene activity across cancers.

Preprint: cohort study in peopleMechanisms

Paper

Cancer/testis antigen expression

Upstream

Latest

Loss of the Y chromosome barely alters tumour gene activity

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