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Biomarker

3 papers

  • Animals3

Funding

18 grants since 2016

Japan Society for the Promotion of ScienceJP¥31.1mAgence Nationale de la Recherche€1.1mNatural Sciences and Engineering Research Council of CanadaCA$76k

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Open Res Europe

Blood pressure control rose with combined care in Uganda

Among adults with human immunodeficiency virus (HIV), blood pressure control rose from 3.6% at baseline to 36.7% after 12 months of combined care.Among adults with human immunodeficiency virus (HIV), blood pressure control rose from 3.6% at baseline to 36.7% after 12 months of combined care.

Preprint: randomised trial in 1,200 adults with HIV and hypertension, 12 monthsInterventions

Limit: Only intervention participants were analysed, without comparison against the trial’s control group

Paper
Research Square

Senescent human skin cells made more protein in the lab

Lab experiments compared human skin cells in senescence—a permanent halt to division—with resting cells and cells that were still dividing.Lab experiments compared human skin cells in senescence—a permanent halt to division—with resting cells and cells that were still dividing.

Preprint: experiments in human dermal fibroblasts, against quiescent and proliferating dermal fibroblastsCellular senescence

Limit: O-propargyl-puromycin labeling served as a proxy for protein production

Paper
Cell

Exercise reshaped gene activity across tissues in mice

An 8-week wheel-running experiment in mice examined 22 tissues and plasma, finding the largest gene-activity changes in skeletal muscle.An 8-week wheel-running experiment in mice examined 22 tissues and plasma, finding the largest gene-activity changes in skeletal muscle.

Experiments in mice, 8 weeksInterventions

Limit: Lifespan and health during aging were not measured

Paper

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