Amyloid burden
Biomarker1 paper1 finding
- Humans1
Associations
1Gray matter brain age
upin humans1
1 study
Gray matter brain age
upin humans1
Gray matter brain age is associated with amyloid burden in humans.
Humansacross the Alzheimer's disease continuumgray matter
Compartment-resolved brain aging reveals distinct vascular and neurodegenerative pathways · Research square · 11 Sep 2026 · Preprint
Latest
3Compartment-resolved brain aging reveals distinct vascular and neurodegenerative pathways
Separating white and gray matter brain age highlights early cardiometabolic risks and divergent links to amyloid and tau pathology.
AnimalsMitochondria
Mitochondrial antioxidant MitoQ reduces Alzheimer's pathology in symptomatic mice
Oral treatment improved behavioral deficits, suppressed amyloid plaques, lowered neuroinflammation, and restored mitochondrial quality control in mice with established disease.
AnimalsBrain aging
Aging rhesus macaques display distinct fluid proteomic signatures of senescence and neuropathology
Plasma proteins tracked aging and amyloid pathology more closely than cerebrospinal fluid across the non-human primate lifespan.