Cerebral oxygen extraction fraction

1. Venous hyperintense signal is associated with cerebral oxygen extraction fraction in humans.

   “We found that VHS was associated with lower OEF and that VHS remained independently associated with reduced OEF in multivariable models adjusting for other vascular parameters.”

   Humanstypically agingbrainn = 36

   Venous arterial spin labeling MRI signal is associated with oxygen supply-independent reduction in cerebral oxygen extraction in typically aging older adults

   Imaging neuroscience (Cambridge, Mass.)·17 Oct 2025

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