Caloric restriction mimetics
Intervention1 paper3 findings
A review describes increased brain autophagy with caloric restriction mimetics, alongside preclinical evidence of improved mitochondrial quality control and increased clearance of amyloid-β, tau, α-synuclein and mutant huntingtin in the brain.
Outcomes
3Mitochondrial quality control
upin reviews1
1 study
Mitochondrial quality control
upin reviews1
Caloric restriction mimetics improve mitochondrial quality control.
Reviewpreclinical evidencebrain
Caloric restriction mimetics rewire the AMPK-mTOR-ULK1 signaling nexus to restore autophagic proteostasis in the aging brain · Molecular and cellular neurosciences · 5 Oct 2026
Clearance of amyloid-β, tau, α-synuclein, and mutant huntingtin
upin reviews1
1 study
Clearance of amyloid-β, tau, α-synuclein, and mutant huntingtin
upin reviews1
Caloric restriction mimetics increase clearance of amyloid-β, tau, α-synuclein, and mutant huntingtin.
Reviewpreclinical evidencebrain
Caloric restriction mimetics rewire the AMPK-mTOR-ULK1 signaling nexus to restore autophagic proteostasis in the aging brain · Molecular and cellular neurosciences · 5 Oct 2026
Autophagy
upin reviews1
1 study
Autophagy
upin reviews1
Caloric restriction mimetics increase autophagy.
Reviewbrain
Caloric restriction mimetics rewire the AMPK-mTOR-ULK1 signaling nexus to restore autophagic proteostasis in the aging brain · Molecular and cellular neurosciences · 5 Oct 2026