Alzheimer's disease dementia

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Journal of Alzheimer's Disease ReportsHumans

Statins cut Alzheimer's risk but raise other dementia risks

A Mendelian randomization analysis found total cholesterol mediated 93.91% of statins' effect on overall dementia and 84.37% on dementia in…A Mendelian randomization analysis found total cholesterol mediated 93.91% of statins' effect on overall dementia and 84.37% on dementia in Alzheimer's disease.

medRxivHumansPreprint

APOE disease risks and proteomic links vary by ancestry

A phenome-wide study of 367,757 All of Us participants linked APOE alleles to 27 phenotypes, finding ancestry-specific risks for dementia and fatty…A phenome-wide study of 367,757 All of Us participants linked APOE alleles to 27 phenotypes, finding ancestry-specific risks for dementia and fatty liver disease.