National Institute of Mental Health

fMRI Studies of Memory and Perception

CollaboratorNo phaseRecruiting2026170 people6 Oct 2026clinicaltrials.gov

First-in-Human Evaluation of [11C]JMJ-129-d2 for PDE-4D Imaging in Healthy Volunteers

Phase 1Recruiting202640 people2 Oct 2026clinicaltrials.gov

NCT07560878

CollaboratorEarly phase 1Recruiting202680 people1 May 2026clinicaltrials.gov

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

Phase 1Recruiting202690 people12 Sept 2025clinicaltrials.gov

NCT07124559

CollaboratorPhase 1/2Not yet recruiting2026144 people15 Aug 2025clinicaltrials.gov

NCT07074899

CollaboratorNo phaseCompleted2025161 people20 Jul 2025clinicaltrials.gov

NCT06580145

CollaboratorPhase 2Recruiting202575 people30 Aug 2024clinicaltrials.gov

NCT06226025

CollaboratorPhase 2Recruiting202450 people26 Jan 2024clinicaltrials.gov

NCT05531591

CollaboratorPhase 4Completed201987 people8 Sept 2022clinicaltrials.gov

NCT05406583

CollaboratorPhase 1Completed202296 people6 Jun 2022clinicaltrials.gov

NCT05388656

CollaboratorPhase 4Completed202240 people24 May 2022clinicaltrials.gov

NCT05062083

Phase 2Terminated20227 people30 Sept 2021clinicaltrials.gov

NCT04225221

CollaboratorPhase 2Completed202010 people13 Jan 2020clinicaltrials.gov

NCT04192266

CollaboratorPhase 3Completed202083 people10 Dec 2019clinicaltrials.gov

NCT04051320

CollaboratorPhase 2Completed202023 people9 Aug 2019clinicaltrials.gov

NCT03973229

CollaboratorEarly phase 1Completed2019127 people4 Jun 2019clinicaltrials.gov

NCT03912428

Phase 1Terminated201931 people11 Apr 2019clinicaltrials.gov

NCT03760458

CollaboratorPhase 1/2Completed202057 people30 Nov 2018clinicaltrials.gov

NCT03689543

Phase 2Completed201974 people28 Sept 2018clinicaltrials.gov

NCT03557684

CollaboratorEarly phase 1Terminated201859 people15 Jun 2018clinicaltrials.gov

Albert R Powers

R01PREMAP - Predictors and Risk Evaluation for Menopause-Associated PsychosisR01MH1317682023–202717 Sept 2026reporter.nih.gov

Yale University

R01PREMAP - Predictors and Risk Evaluation for Menopause-Associated PsychosisR01MH131768US$415.1k2023–202717 Sept 2026reporter.nih.gov

Kalen J. Petersen

K01BIOLOGICAL AGING AND COGNITIVE IMPAIRMENT IN PERSONS WITH HIVK01MH1368622024–202917 Sept 2026reporter.nih.gov

Washington University

K01BIOLOGICAL AGING AND COGNITIVE IMPAIRMENT IN PERSONS WITH HIVK01MH136862US$173.1k2024–202917 Sept 2026reporter.nih.gov

Esti Iturralde

K23Optimizing Care to Prevent Diabetes and Promote Cardiovascular Health Among Younger Adults with Severe Mental IllnessK23MH1260782022–202717 Sept 2026reporter.nih.gov

Kaiser Foundation Research Institute

K23Optimizing Care to Prevent Diabetes and Promote Cardiovascular Health Among Younger Adults with Severe Mental IllnessK23MH126078US$188.3k2022–202717 Sept 2026reporter.nih.gov

Rachel Manber

R01Targeting Insomnia to Prevent Depression in the Menopause TransitionR01MH1415372026–203117 Sept 2026reporter.nih.gov

Fiona C Baker

R01Targeting Insomnia to Prevent Depression in the Menopause TransitionR01MH1415372026–203117 Sept 2026reporter.nih.gov

SRI International

R01Targeting Insomnia to Prevent Depression in the Menopause TransitionR01MH141537US$1.3m2026–203117 Sept 2026reporter.nih.gov

Hadine Joffe

R01Using allopregnanolone to probe behavioral and neurobiological mechanisms that underlie depression in women across perimenopausal stageR01MH1286172022–202716 Sept 2026reporter.nih.gov

Katherine Elizabeth Burdick

R01Using allopregnanolone to probe behavioral and neurobiological mechanisms that underlie depression in women across perimenopausal stageR01MH1286172022–202716 Sept 2026reporter.nih.gov

Beth Israel Deaconess Medical Center

R01Using allopregnanolone to probe behavioral and neurobiological mechanisms that underlie depression in women across perimenopausal stageR01MH128617US$900.5k2022–202716 Sept 2026reporter.nih.gov

Katharine Natasha Thakkar

R01Gene x Ovarian Hormone Interactions in Perimenopausal Risk for PsychosisR01MH1405272026–203110 Sept 2026reporter.nih.gov

Kelly L Klump

R01Gene x Ovarian Hormone Interactions in Perimenopausal Risk for PsychosisR01MH1405272026–203110 Sept 2026reporter.nih.gov

Kristen Culbert

R01Gene x Ovarian Hormone Interactions in Perimenopausal Risk for PsychosisR01MH1405272026–203110 Sept 2026reporter.nih.gov

Shaunna L Clark

R01Gene x Ovarian Hormone Interactions in Perimenopausal Risk for PsychosisR01MH1405272026–203110 Sept 2026reporter.nih.gov

Michigan State University

R01Gene x Ovarian Hormone Interactions in Perimenopausal Risk for PsychosisR01MH140527US$796.1k2026–203110 Sept 2026reporter.nih.gov

Ellen Eun-Ok Lee

R01Aging with Schizophrenia: A Multi-site Investigation of the Effects of Sleep Disturbances on Brain Connectivity and Cognitive FunctioningR01MH1400052026–20319 Sept 2026reporter.nih.gov

Bengi Baran

R01Aging with Schizophrenia: A Multi-site Investigation of the Effects of Sleep Disturbances on Brain Connectivity and Cognitive FunctioningR01MH1400052026–20319 Sept 2026reporter.nih.gov

University of Iowa

R01Aging with Schizophrenia: A Multi-site Investigation of the Effects of Sleep Disturbances on Brain Connectivity and Cognitive FunctioningR01MH140005US$775.8k2026–20319 Sept 2026reporter.nih.gov

Association between plasma brain-derived p-tau variants and anxiety phenotypes in older adults

R01 MH108509, T32 MH0199865 Oct 2026api.crossref.org

Prevalence of abnormal spirometry and correlates of lung function decline among a population in rural Uganda

R01MH1256672 Oct 2026pubmed.ncbi.nlm.nih.gov

Somatic mutations and single-nucleus transcriptomics reveal uniquely human properties of neuronal aging

R01MH13480924 Sept 2026api.crossref.org

Increasing Multimorbidity Burden After COVID-19 Infection Among People With and Without HIV in the United States: Insights From the National Clinical Cohort Collaborative (N3C)

R01MH13154218 Sept 2026pubmed.ncbi.nlm.nih.gov

Cardiovascular health and depression among postpartum women in the United States

R01MH12031318 Jul 2026api.crossref.org

Censoring-Aware Reinforcement Learning to Optimize Early Risk Alerts from Longitudinal Clinical Data

K01MH1273091 Jan 2026pubmed.ncbi.nlm.nih.gov

The GrimAge clock corresponds to brain ageing and social determinants of health in people with HIV

EBioMedicine24 Sept 2026