Sleep latency

Biomarker

3 papers8 findings

  • Humans2

Interventions

3

Moderate physical activity

no changein humans1

1 study
  1. Moderate physical activity has no effect on sleep latency in humans (B = 0.04).

    “Moderate activity showed no significant association (B = 0.04, SD = 0.11, 95% CI [-0.17, 0.26]).”

    Humansmild cognitive impairment14 daysn = 7

    Sleep Latency and Physical Activity in Older Adults with Mild Cognitive Impairment: Oura Ring Longitudinal Study

    GSA 2025 abstract31 Dec 2025

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Vigorous physical activity

downin humans1

1 study
  1. Vigorous physical activity decreases sleep latency in humans (-0.60 second per second).

    “Each additional second of vigorous activity corresponded to a 0.60 second decrease in latency (B = -0.60, SD = 0.21, p < .01, CI [-1.02, -0.18]).”

    Humansmild cognitive impairment14 daysn = 7

    Sleep Latency and Physical Activity in Older Adults with Mild Cognitive Impairment: Oura Ring Longitudinal Study

    GSA 2025 abstract31 Dec 2025

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Caffeine

upin humans1

1 study
  1. Caffeine increases sleep latency in humans.

    “Caffeine typically prolonged sleep latency, reduced total sleep time and sleep efficiency, and worsened perceived sleep quality.”

    Review

    Coffee, caffeine, and sleep: A systematic review of epidemiological studies and randomized controlled trials

    Sleep medicine reviews30 Jan 2016

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Effects

2

Amyloid burden

no changein humans1

1 study
  1. Sleep latency has no effect on amyloid burden in humans (β = 0.257, p = 0.324).

    “amyloid: β = 0.257, p = 0.324).”

    Humansessential tremorbrainn = 24

    Assessing Change in Sleep Latency as a Potential Indicator of Alzheimer’s Pathologies in Essential Tremor

    GSA 2025 abstract31 Dec 2025

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Tau pathology

no changein humans1

1 study
  1. Sleep latency has no effect on tau pathology in humans (β = 0.129, p = 0.664).

    “when examined in an adjusted regression, the change in sleep latency was not associated with pathological outcomes (tau: β = 0.129, p = 0.664”

    Humansessential tremorbrainn = 24

    Assessing Change in Sleep Latency as a Potential Indicator of Alzheimer’s Pathologies in Essential Tremor

    GSA 2025 abstract31 Dec 2025

More on Tau pathology

Associations

3

Amyloid burden

upin humans1

1 study
  1. Sleep latency is associated with amyloid burden in humans (r = 0.448, p = 0.028).

    “amyloid burden (r = 0.448, p = 0.028)”

    Humansessential tremorbrainn = 24

    Assessing Change in Sleep Latency as a Potential Indicator of Alzheimer’s Pathologies in Essential Tremor

    GSA 2025 abstract31 Dec 2025

More on Amyloid burden

Tau pathology

upin humans1

1 study
  1. Sleep latency is associated with tau pathology in humans (r = 0.473, p = 0.023).

    “Correlational findings indicate an association between increased sleep latency and tau pathology (r = 0.473, p = 0.023)”

    Humansessential tremorbrainn = 24

    Assessing Change in Sleep Latency as a Potential Indicator of Alzheimer’s Pathologies in Essential Tremor

    GSA 2025 abstract31 Dec 2025

More on Tau pathology

Light physical activity

no changein humans1

1 study
  1. Light physical activity is associated with sleep latency in humans (-0.02 seconds per second).

    “Light activity showed a near significant reduction of 0.02 seconds per second (B = -0.02, SD = 0.01, 95% CI [-0.05, 0.01]).”

    Humansmild cognitive impairment14 daysn = 7

    Sleep Latency and Physical Activity in Older Adults with Mild Cognitive Impairment: Oura Ring Longitudinal Study

    GSA 2025 abstract31 Dec 2025

More on Light physical activity

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