Cognitive impairment no dementia

Disease2 papers3 findings

  • Humans2

Associations

3

Hearing impairment

upin humans1HR 1.16Low certainty

1 study
  1. Hearing impairment raises the risk of cognitive impairment no dementia in humans (HR 1.16 (95% CI, 1.07-1.25)).

    Humanscompared with no sensory impairment

    Sensory impairment and cognitive-state transitions in middle-aged and older adults: a multistate Markov analysis of the health and retirement study · Frontiers in aging neuroscience · 7 Sep 2026

Hearing impairment →

Visual impairment

upin humans1HR 1.18Low certainty

1 study
  1. Visual impairment raises the risk of cognitive impairment no dementia in humans (HR 1.18 (95% CI, 1.10-1.27)).

    Humanscompared with no sensory impairment

    Sensory impairment and cognitive-state transitions in middle-aged and older adults: a multistate Markov analysis of the health and retirement study · Frontiers in aging neuroscience · 7 Sep 2026

Visual impairment →

Dual sensory impairment

upin humans1HR 1.37Low certainty

1 study
  1. Dual sensory impairment raises the risk of cognitive impairment no dementia in humans (HR 1.37 (95% CI, 1.26-1.50)).

    Humanscompared with no sensory impairment

    Sensory impairment and cognitive-state transitions in middle-aged and older adults: a multistate Markov analysis of the health and retirement study · Frontiers in aging neuroscience · 7 Sep 2026

Dual sensory impairment →

Latest

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American Journal of Public HealthHumans

Earlier family loss links to higher cognitive impairment risk

A 20-year longitudinal study finds earlier family bereavement is tied to higher cognitive impairment risk, with child loss remaining robust after…A 20-year longitudinal study finds earlier family bereavement is tied to higher cognitive impairment risk, with child loss remaining robust after health adjustments.

Age and AgeingHumans

Immune cell profiles predict cognitive decline in older adults

In 4,464 cognitively normal older adults, a higher immune risk score predicted incident cognitive impairment or dementia with a hazard ratio of 1.63…In 4,464 cognitively normal older adults, a higher immune risk score predicted incident cognitive impairment or dementia with a hazard ratio of 1.63 over six years.

Alzheimer's & DementiaHumans

WTC neurotoxicant exposure links to cortical thinning

In 218 responders and controls aged 44 to 65, cortical thickness was associated with the WTC exposure severity index at R = -0.38.In 218 responders and controls aged 44 to 65, cortical thickness was associated with the WTC exposure severity index at R = -0.38.