Cell-transfer experiments in mice lacking lymphoid immune cells found that regulatory immune cells rescued regeneration inhibited by another immune-cell type.Cell-transfer experiments in mice lacking lymphoid immune cells found that regulatory immune cells rescued regeneration inhibited by another immune-cell type.
Experiments in lymphoid-deficient mutant mice, against mice receiving CD8 T cellsImmune response
Limit: The experiments did not assess how aging affects digit-tip regeneration
Genetic analyses using two European-ancestry datasets linked higher genetically predicted levels of placental alkaline phosphatase, a protein, to greater risk of spinal…Genetic analyses using two European-ancestry datasets linked higher genetically predicted levels of placental alkaline phosphatase, a protein, to greater risk of spinal canal narrowing.
Mendelian randomisation in people of European ancestryInterventions
Limit: Possible overlap between protein and UK Biobank samples could bias the genetic association