Ischemic stroke
Disease16 papers8 findingsMeSH D000083242
- Humans14
Interventions
1Air pollution
no changein humans1
1 study
Air pollution
no changein humans1
Air pollution has no effect on ischemic stroke in humans.
“In contrast, no significant associations were observed between air pollution metrics and ischemic stroke.”
Humans17.6 years
Long-term PM2.5 exposure and incident heart failure in the UK Biobank: relative and absolute risk estimates · Frontiers in public health · 14 Sep 2026
Associations
7Covert brain infarction
upin humans1
1 study
Covert brain infarction
upin humans1
Covert brain infarction raises the risk of ischemic stroke in humans.
Review
International Modified Delphi Consensus on Assessment and Management of Covert Brain Infarction · International journal of stroke : official journal of the International Stroke Society · 2 Oct 2026
CXCL10
upin humans1HR 1.19
1 study
CXCL10
upin humans1HR 1.19
CXCL10 raises the risk of ischemic stroke in humans (HR 1.19; 95%CI 1.01-1.41).
Humansmedian of 14 yearsn = 1,175
Plasma CXCL10 links to higher stroke risk in older adults · Translational stroke research · 2 Oct 2026
Particulate matter
upin humans1HR 1.29
1 study
Particulate matter
upin humans1HR 1.29
Particulate matter raises the risk of ischemic stroke in humans (HR 1.29, 95% CI 1.15-1.45).
Humansin UK Biobankevery 5 μg/m3 increment
Air pollution links to stroke risk in two population cohorts · Neuroepidemiology · 29 Sep 2026
Household air pollution
downin humans1HR 0.949
1 study
Household air pollution
downin humans1HR 0.949
Household air pollution is associated with ischemic stroke in humans (HR 0.949, 95% CI 0.911–0.989).
Humansn = 390,197
Household cooking fuel, kitchen ventilation, and incident hemorrhagic stroke in Chinese adults: a prospective cohort study · Research Square · 27 Sep 2026 · Preprint
Serum uric acid
upin humans1
1 study
Serum uric acid
upin humans1
Serum uric acid raises the risk of ischemic stroke in humans.
HumansSUA exceeding 330 μmol/L in diabetic patients
Nonlinear Association Between Serum Uric Acid and Incident Stroke in Patients with Diabetes: A Two-Centre Cohort Study · International journal of general medicine · 22 Sep 2026
Polygenic risk score
upin humans1
1 study
Polygenic risk score
upin humans1
Polygenic risk score predicts ischemic stroke in humans (OR/SD = 1.24, 95% CI 1.12-1.36, R 2 = 2.42%).
“Among EA participants, SBayesRC demonstrated the largest effect size and liability R 2 in the REGARDS holdout validation cohort (OR/SD = 1.24, 95% CI 1.12-1.36, R 2 = 2.42%).”
HumansREGARDS holdout validation cohort
Evaluation of functional annotation-informed and ancestry-specific polygenic risk scores for ischemic stroke · Frontiers in bioinformatics · 10 Sep 2026
LDL-C
downin humans1
1 study
LDL-C
downin humans1
LDL-C lowers the risk of ischemic stroke in humans.
Reviewin patients with atherosclerotic stroke
Optimal LDL-C Levels for Ischemic Stroke Prevention: A Neurologist's Perspective · Journal of lipid and atherosclerosis · 27 May 2026
Latest
19Association of pre-transplant electrocardiogram with long-term cardiovascular events in liver transplant recipients
Plasma CXCL10 links to higher stroke risk in older adults
Each 1-standard deviation higher CXCL10 was linked to 20% greater stroke risk over a median follow-up of 14 years.Each 1-standard deviation higher CXCL10 was linked to 20% greater stroke risk over a median follow-up of 14 years.
Early ablation lowers cardiac risks in stroke patients with AF
At 36 months, early ablation yielded a 1.54-month gain in event-free survival and an 11.17% absolute risk reduction in major adverse cardiovascular…At 36 months, early ablation yielded a 1.54-month gain in event-free survival and an 11.17% absolute risk reduction in major adverse cardiovascular events versus medical therapy.
International Modified Delphi Consensus on Assessment and Management of Covert Brain Infarction
Social context predicts heart risks despite normal biomarkers
Below target cutoffs, participants with less favorable social context had cardiovascular event rates of 3.39 versus 1.68, 7.16 versus 2.05, and 8.67…Below target cutoffs, participants with less favorable social context had cardiovascular event rates of 3.39 versus 1.68, 7.16 versus 2.05, and 8.67 versus 2.34 per 1,000 person-years.
Estimated sdLDL-C predicts cardiovascular risk in Japanese adults
In over 1.8 million Japanese adults, the highest quartile of estimated sdLDL-C carried an ASCVD hazard ratio of 1.25 compared with the lowest.In over 1.8 million Japanese adults, the highest quartile of estimated sdLDL-C carried an ASCVD hazard ratio of 1.25 compared with the lowest.
GLP-1 receptor agonists link to lower stroke and Alzheimer risk
A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced…A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced risk of stroke and Alzheimer disease.