Atrial fibrillation
Disease27 papers19 findingsMeSH D001281
Human cohort studies link atrial fibrillation to higher risk of out-of-hospital cardiac arrest, driven by genetic, multi-biomarker, artificial intelligence electrocardiogram, sleep, and structural cardiac risk factors. Reviews also note predictive roles for machine learning and photoplethysmography.
- Humans19
- In silico2
Associations
17Multi-biomarker risk score
upin humans1HR 2.72
1 study
Multi-biomarker risk score
upin humans1HR 2.72
Multi-biomarker risk score predicts atrial fibrillation in humans.
Humansbeyond CHARGE-AF
Biomarker score with ketone bodies predicts atrial fibrillation · Progress in cardiovascular diseases · 30 Sep 2026
Multi-biomarker risk score is associated with atrial fibrillation in humans.
Humans16.4 years
Biomarker score with ketone bodies predicts atrial fibrillation · Progress in cardiovascular diseases · 30 Sep 2026
Multi-biomarker risk score raises the risk of atrial fibrillation in humans (HR 2.72, 95% CI, 2.11-3.49).
Humansversus Very Low Risk Score = 016.4 years
Biomarker score with ketone bodies predicts atrial fibrillation · Progress in cardiovascular diseases · 30 Sep 2026
Machine-learning
upin humans1
1 study
Machine-learning
upin humans1
machine-learning predicts atrial fibrillation in humans.
Review
[Atrial fibrillation screening-reading the P-wave] · Innere Medizin (Heidelberg, Germany) · 2 Oct 2026
P-wave duration
upin humans1
1 study
P-wave duration
upin humans1
P-wave duration predicts atrial fibrillation in humans.
Review
[Atrial fibrillation screening-reading the P-wave] · Innere Medizin (Heidelberg, Germany) · 2 Oct 2026
Omega-3 fatty acids
upin reviews1
1 study
Omega-3 fatty acids
upin reviews1
Omega-3 fatty acids raise the risk of atrial fibrillation.
Reviewhigh-dose formulations in high-risk populations
Diet and Risk of Cardiovascular Disease · The American journal of medicine · 1 Oct 2026
Obstructive sleep apnea
upin humans1
1 study
Obstructive sleep apnea
upin humans1
Obstructive sleep apnea raises the risk of atrial fibrillation in humans.
Humansin underweight with low waist circumference and severe obesity with high waist circumference groups
Long-Term Cardiovascular Outcomes of Obstructive Sleep Apnea by Adiposity Phenotype: A Korean Nationwide Cohort Study · Research Square · 29 Sep 2026 · Preprint
Retinal nerve fiber layer asymmetry
upin humans1
1 study
Retinal nerve fiber layer asymmetry
upin humans1
Retinal nerve fiber layer asymmetry raises the risk of atrial fibrillation in humans (HR ~1.07 per SD increase).
Humansn = 46,836
Intereye retinal asymmetry is linked to cardiovascular risk · Journal of the American Heart Association · 29 Sep 2026
Forced vital capacity
downin humans1OR 0.351
1 study
Forced vital capacity
downin humans1OR 0.351
Forced vital capacity lowers the risk of atrial fibrillation in humans (OR 0.351, 95% CI 0.167-0.736).
Humanscompared with normal FVCn = 2,408
Supranormal lung function and incident atrial fibrillation · Pulmonology · 25 Sep 2026
Forced expiratory volume in 1 second
downin humans1OR 0.42
1 study
Forced expiratory volume in 1 second
downin humans1OR 0.42
Forced expiratory volume in 1 second lowers the risk of atrial fibrillation in humans (OR 0.420, 95% CI 0.198-0.888).
Humanscompared with normal FEV 1n = 2,408
Supranormal lung function and incident atrial fibrillation · Pulmonology · 25 Sep 2026
Out-of-hospital cardiac arrest
upin humans1
1 study
Out-of-hospital cardiac arrest
upin humans1
Atrial fibrillation raises the risk of out-of-hospital cardiac arrest in humans (0.61% [95% CI: 0.58-0.64%] vs 0.50% normal).
Humans5 years
Electrocardiogram Abnormalities and the Risk of Out-of-Hospital Cardiac Arrest: A Nationwide Cohort Study · Heart rhythm · 25 Sep 2026
AI-ECG age gap
upin humans1HR 1.37
1 study
AI-ECG age gap
upin humans1HR 1.37
AI-ECG age gap raises the risk of atrial fibrillation in humans (HR 1.37, 95% CI: 1.24-1.51).
“AF-PRS (HR 1.61, 95% CI: 1.48-1.76) and the AI-ECG age gap (HR 1.37, 95% CI: 1.24-1.51) were independently associated with incident AF.”
Humansincident AFn = 39,478
Prediction of Atrial Fibrillation Risk Through the Integration of Genetic Information and Artificial Intelligence-Based Electrocardiogram Data · Journal of arrhythmia · 24 Sep 2026
All 17Fewer
AF-PRS
upin humans1HR 1.61
1 study
AF-PRS
upin humans1HR 1.61
AF-PRS raises the risk of atrial fibrillation in humans (HR 1.61, 95% CI: 1.48-1.76).
“AF-PRS (HR 1.61, 95% CI: 1.48-1.76) and the AI-ECG age gap (HR 1.37, 95% CI: 1.24-1.51) were independently associated with incident AF.”
Humansincident AFn = 39,478
Prediction of Atrial Fibrillation Risk Through the Integration of Genetic Information and Artificial Intelligence-Based Electrocardiogram Data · Journal of arrhythmia · 24 Sep 2026
Photoplethysmography
upin humans1
1 study
Photoplethysmography
upin humans1
Photoplethysmography predicts atrial fibrillation in humans.
“AI-based PPG may support blood pressure estimation, atrial fibrillation detection, sleep and respiratory monitoring, vascular aging assessment, pulmonary hypertension screening, preeclampsia assessment, volume-status and compensatory-reserve assessment”
Review
Artificial Intelligence Enabled Diagnostics Using Photoplethysmography (PPG): Beyond SpO₂ and Heart Rate · Life (Basel, Switzerland) · 15 Sep 2026
Healthcare access
downin humans1
1 study
Healthcare access
downin humans1
healthcare access is associated with atrial fibrillation in humans.
Humans11.5 yearsn = 3,240
Socioeconomic status, healthcare access, and risk of atrial fibrillation: an investigation using the Jackson Heart Study Research Materials · medRxiv : the preprint server for health sciences · 10 Sep 2026 · Preprint
Income
downin humans1HR 0.61
1 study
Income
downin humans1HR 0.61
income lowers the risk of atrial fibrillation in humans (HR 0.61, 95% CI 0.47, 0.78).
Humans11.5 yearsn = 3,240
Socioeconomic status, healthcare access, and risk of atrial fibrillation: an investigation using the Jackson Heart Study Research Materials · medRxiv : the preprint server for health sciences · 10 Sep 2026 · Preprint
Left ventricular dysfunction
upin humans1
1 study
Left ventricular dysfunction
upin humans1
Left ventricular dysfunction raises the risk of atrial fibrillation in humans (19.9% vs 4.1%).
“One-year incidence rose from 4.1% (both negative) to 9.8% (LVSD-positive only), 20.1% (LVDD-positive only), and 19.9% (both positive).”
Humanspatients in sinus rhythm
Artificial Intelligence-Enabled Electrocardiography Model for Left Ventricular Systolic and Diastolic Dysfunction Predict Incident Atrial Fibrillation in Patients with Sinus Rhythm: A Time-Dependent Analysis · Diagnostics (Basel, Switzerland) · 8 Sep 2026
AI-ECG LVDD score
upin humans1
1 study
AI-ECG LVDD score
upin humans1
AI-ECG LVDD score predicts atrial fibrillation in humans (AUROC 0.817).
“more steeply for LVSD (AUROC 0.803 at 30 days to 0.713 at 365 days) than LVDD (0.817 to 0.764)”
Humans30 days
Artificial Intelligence-Enabled Electrocardiography Model for Left Ventricular Systolic and Diastolic Dysfunction Predict Incident Atrial Fibrillation in Patients with Sinus Rhythm: A Time-Dependent Analysis · Diagnostics (Basel, Switzerland) · 8 Sep 2026
AI-ECG LVSD score
upin humans1
1 study
AI-ECG LVSD score
upin humans1
AI-ECG LVSD score predicts atrial fibrillation in humans (AUROC 0.803).
“more steeply for LVSD (AUROC 0.803 at 30 days to 0.713 at 365 days) than LVDD (0.817 to 0.764)”
Humans30 days
Artificial Intelligence-Enabled Electrocardiography Model for Left Ventricular Systolic and Diastolic Dysfunction Predict Incident Atrial Fibrillation in Patients with Sinus Rhythm: A Time-Dependent Analysis · Diagnostics (Basel, Switzerland) · 8 Sep 2026
Latest
29Association of pre-transplant electrocardiogram with long-term cardiovascular events in liver transplant recipients
Early ablation lowers cardiac risks in stroke patients with AF
At 36 months, early ablation yielded a 1.54-month gain in event-free survival and an 11.17% absolute risk reduction in major adverse cardiovascular…At 36 months, early ablation yielded a 1.54-month gain in event-free survival and an 11.17% absolute risk reduction in major adverse cardiovascular events versus medical therapy.
Biomarker score with ketone bodies predicts atrial fibrillation
A high biomarker score carried nearly threefold greater atrial fibrillation risk than a very low score (HR 2.72; 95% CI, 2.11-3.49).A high biomarker score carried nearly threefold greater atrial fibrillation risk than a very low score (HR 2.72; 95% CI, 2.11-3.49).