Particulate matter
Intervention4 papers4 findings
- Humans3
Outcomes
1Cognitive decline
no changein humans1
1 study
Cognitive decline
no changein humans1
Particulate matter has no effect on cognitive decline in humans.
Humansafter adjustment for annual mean air pollutant exposure
High nitrogen dioxide days linked to faster cognitive decline · medRxiv · 29 Sep 2026 · Preprint
Associations
3Ischemic stroke
upin humans1HR 1.29
1 study
Ischemic stroke
upin humans1HR 1.29
Particulate matter raises the risk of ischemic stroke in humans (HR 1.29, 95% CI 1.15-1.45).
Humansin UK Biobankevery 5 μg/m3 increment
Air pollution links to stroke risk in two population cohorts · Neuroepidemiology · 29 Sep 2026
Stroke
upin humans1OR 1.31
1 study
Stroke
upin humans1OR 1.31
Particulate matter raises the risk of stroke in humans (OR 1.31, 95% CI 1.08-1.59).
Humansin CHARLS
Air pollution links to stroke risk in two population cohorts · Neuroepidemiology · 29 Sep 2026
Dementia
upin humans1
1 study
Dementia
upin humans1
Particulate matter raises the risk of dementia in humans.
“long-term exposure to particulate matter (PM 2.5 ), nitrogen oxides (NO 2 ), and black carbon was associated with increased dementia risk”
Reviewlong-term
Environmental Pollution, Biomarkers, and Dementia: An Evidence Review · International journal of molecular sciences · 15 Sep 2026
Latest
4High nitrogen dioxide days linked to faster cognitive decline
Comparing the 75th percentile with the median of nitrogen dioxide exceedance days, 14-year decline was -0.09 SD for memory and -0.10 SD for fluency.Comparing the 75th percentile with the median of nitrogen dioxide exceedance days, 14-year decline was -0.09 SD for memory and -0.10 SD for fluency.
Proteomics reveals how air pollutants drive chronic disease
In 48,645 UK Biobank participants, plasma proteomic profiles showed shared immune pathways and pollutant-specific mechanisms linking air pollution to…In 48,645 UK Biobank participants, plasma proteomic profiles showed shared immune pathways and pollutant-specific mechanisms linking air pollution to mortality and chronic disease risks.
Air pollution links to stroke risk in two population cohorts
In UK Biobank, every 5 µg/m³ increment in PM2.5 carried an incident ischemic stroke hazard ratio of 1.29, reaching 1.44 alongside high genetic…In UK Biobank, every 5 µg/m³ increment in PM2.5 carried an incident ischemic stroke hazard ratio of 1.29, reaching 1.44 alongside high genetic susceptibility.