Partial reprogramming research news

YesterdayFri 2 OctFriday 2 October4 papers

Enhanced liver regeneration via targeted mRNA delivery for partial in vivo reprogramming

MiceCell reports. MedicineYesterday

Pharmacological control of inflammation via innate immune memory manipulation

ReviewCurrent opinion in pharmacologyYesterday

Beyond survival: psychoneuroimmunology-driven cancer psychological rehabilitation-a paradigm shift from symptom management to biobehavioral remodeling

ReviewFrontiers in oncologyYesterday

Mechanisms of resistance to PARP inhibitors in advanced epithelial ovarian cancer: biological determinants and therapeutic implications

ReviewFrontiers in oncologyYesterday

Thu 1 Oct2 papers

Extrachromosomal DNA as a platform for epigenetic reprogramming in cancer

ReviewMolecular cancer1 Oct

Unravelling therapeutic resistance: role of cancer stem cell and microRNA in metastatic prostate cancer

ReviewFrontiers in molecular biosciences1 Oct

Wed 30 Sep3 papers

The BCG Vaccine: Pharmacological Biotechnology and Expanding Immunological Horizons

ReviewFrontiers in bioscience (Elite edition)30 Sep

STC2 promotes cisplatin resistance through metabolic reprogramming and lactylation-mediated epigenetic regulation in cervical cancer

HumansActa biochimica et biophysica Sinica30 Sep

Epigenetic progression of pancreatic cancer to aggressive subtypes involves alternate routes of lineage reprogramming in subtype-intermediate progenitor cells

HumansPreprintbioRxiv30 Sep

Tue 29 Sep2 papers

Traditional Chinese Medicine Formulas in Delaying Aging: From Theoretical Foundations to Molecular Mechanisms and Translational Perspectives

ReviewJournal of cellular and molecular medicine29 Sep

A metabolic-epigenetic switch governs multicellular cardiac repair following succinate dehydrogenase inhibition

CellsNature cardiovascular research29 Sep

Mon 28 Sep7 papers

Epigenetic reprogramming in cadmium-associated liver injury: Evidence, mechanistic insights, and therapeutic perspectives

ReviewEnvironmental toxicology and pharmacology28 Sep

Harnessing Medicinal Plants Through Advanced Drug Delivery: A New Era in Type 2 Diabetes Management

ReviewPharmaceutics28 Sep

Developmental and Molecular Insights into AgNO<sub>3</sub>-Induced Partial Masculinization and Stamen Abortion in <i>Siraitia grosvenorii</i> C. Jeffrey ex A.M. Lu and Zhi Y. Zhang

ResearchPlants (Basel, Switzerland)28 Sep

Environmental Exposures and Epigenetic Remodeling in Supraventricular Tachycardias: What Atrial Fibrillation Can and Cannot Tell Us

ReviewLife (Basel, Switzerland)28 Sep

CRISPR Technologies in Type 2 Diabetes: From Mechanistic Insights to Therapeutic Discovery

ReviewInternational journal of molecular sciences28 Sep

Targeted Intracellular Metal Modulation Attenuates Oxidative Stress and Preserves Retinal Integrity and Function in a Zebrafish Model of Mitochondrial Dysfunction and Age-Related Retinal Degeneration

FishInternational journal of molecular sciences28 Sep

HMGB1 Post-Translational Modifications in Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma: Current Evidence, Emerging Mechanistic Concepts, and Unresolved Questions

ReviewInternational journal of molecular sciences28 Sep

Sat 26 Sep5 papers

Molecular Signaling Pathways, Regulatory and Coactivator Networks, and Emerging Mechanisms in Hepatocellular Carcinoma

ReviewBiomedicines26 Sep

Aging Biology of Bone-to-Tendon Healing and the Epigenetic Clock: A Biological-Age Readout of Rotator Cuff Healing Capacity

ReviewBiomedicines26 Sep

Bridging BET bromodomain and immune checkpoint inhibitors through generative bioorganic frameworks for next-generation cancer immunotherapy

ReviewRSC medicinal chemistry26 Sep

Epigenetic mechanisms in traumatic brain injury: a focus on astrocytes and therapeutic implications

ReviewJournal of neuroinflammation26 Sep

Inhibition of Histone Methyltransferase G9a Hampers Early Embryonic Development through Disruption of Epigenetic Reprogramming and Transcriptomic Homeostasis

CellsPreprintResearch Square26 Sep

Fri 25 Sep7 papers

Integrated cellular and molecular mechanisms of neuropsychiatric dysfunction in polycystic ovary syndrome

ReviewJournal of psychiatric research25 Sep

Potential Determinants of Progression from Cough-Variant Asthma to Classic Asthma in Children: Evidence, Mechanisms, and Clinical Research Gaps

ReviewJournal of asthma and allergy25 Sep

ISP 3 Platform powered by Geneformer: Framework for Cross-Species, Sequential, and Multi-Gene In Silico Perturbation Screens with Application to iPS Cell State Transitions

In silicoPreprintbioRxiv25 Sep

Genome-wide DNA methylation analysis of the liver in adult guinea pigs born preterm and term highlights the importance Cry1 and circadian rhythm in males

ResearchPreprintResearch Square25 Sep

Abasic site repair in APE1-deficient mouse embryonic stem cells: a matter for the MRN complex and ATM signaling

MiceNucleic acids research25 Sep

Maternal TRIM28 safeguards bovine embryonic genome activation by regulating SAM-dependent methylation via lipid metabolism

HumansHuman reproduction (Oxford, England)25 Sep

Aging as Loss of Biological Self-Correction: A Geroscience Framework for Longevity, Inflammaging, and Restored Resilience

ReviewGeriatrics (Basel, Switzerland)25 Sep

Thu 24 Sep5 papers

DNMT1-Mediated Epigenetic Reprogramming Drives KMT2A Amplifications and Rearrangements

ResearchPreprintbioRxiv24 Sep

TEgment dissects transposable element reactivation upon CDK9 inhibition in acute myeloid leukemia

ResearchPreprintbioRxiv24 Sep

Targeting MAT2A-S-adenosylmethionine (SAM) Axis Attenuates DNA Damage Response and Cancer Stemness to Increase Platinum Sensitivity in Ovarian Cancer

HumansPreprintbioRxiv24 Sep

Stepwise direct reprogramming of adult human dermal fibroblasts into tendon-like cells via transcription factor optimization and 3D culture

CellsPreprintResearch Square24 Sep

BORIS in Hormone-Driven Cancers: Epigenetic Reprogramming, Transcriptional Plasticity, and Therapeutic Implications

ResearchPreprintPreprints.org24 Sep

Wed 23 Sep4 papers

Expression GWAS and Differential Methylome Profiling Reveal Upstream Regulators of Drought Memory Genes in Arabidopsis thaliana

ResearchPlant, cell & environment23 Sep

Persistent Epigenetic Reprogramming Is Associated With Contrasting Drought-Response Strategies in Citrus Scion-Rootstock Systems

ResearchPhysiologia plantarum23 Sep

Selective MicroRNA Dysregulation in IPF-Derived Mesenchymal Stromal Cells Suggests Restricted Regulatory Remodeling

HumansFASEB journal : official publication of the Federation of American Societies for Experimental Biology23 Sep

The telomere-to-telomere gap-free reference genome and DNA methylome unveil epigenetic regulation of proanthocyanidin biosynthesis during apricot fruit development

ResearchThe Plant journal : for cell and molecular biology23 Sep

Tue 22 Sep1 paper

Genetic dissection of one-carbon metabolism: Roles in pluripotency and embryonic development

ReviewDevelopmental biology22 Sep

Sun 20 Sep1 paper

Generation of an induced pluripotent stem cell line, JHUi010-A, from an arrhythmogenic cardiomyopathy patient harboring pathogenic DSG2 variant c.2358delA

CellsStem cell research20 Sep

Sat 19 Sep5 papers

Autophagy inhibition sensitizes radiotherapy responses in high-grade mutant IDH1 glioma

MiceNature communications19 Sep

Dormancy and reactivation of disseminated tumor cells: From molecular mechanisms to therapeutic implications

ReviewGene19 Sep

Histone modifications and chromatin landscapes in microglial function: Developmental imprinting and disease-associated reprogramming

ReviewAgeing research reviews19 Sep

Placental dysfunction drives fetal growth restriction: mechanisms and translational perspectives

ReviewFrontiers in molecular biosciences19 Sep

Molecular reprogramming in cutaneous melanoma: the central role of G9a and EZH2 methyltransferase inhibitors in tumor plasticity, immune evasion, and therapeutic resistance

ReviewFrontiers in pharmacology19 Sep

Fri 18 Sep1 paper

Mechanistic Pathways of Wound Healing: From Hemostasis to Scar-Free Regeneration

ReviewCell biochemistry and function18 Sep

Thu 17 Sep3 papers

HBV induces immunosuppressive macrophages via metabolic and epigenetic reprogramming to facilitate the establishment of chronic persistent infection

HumansGut17 Sep

DNA replication is dispensable for developmental progression, but required for heterochromatin organization at mouse zygotic genome activation

MicePreprintbioRxiv17 Sep

Maternal high-fat diet and risk of cardiovascular disease in offspring: a review of mechanisms, controversies, and interventions

ReviewExperimental biology and medicine (Maywood, N.J.)17 Sep

YesterdayFri 2 OctFriday 2 October· 4 papers

Thu 1 Oct· 2 papers

Wed 30 Sep· 3 papers

Tue 29 Sep· 2 papers

Mon 28 Sep· 7 papers

Sat 26 Sep· 5 papers

Fri 25 Sep· 7 papers

Thu 24 Sep· 5 papers

Wed 23 Sep· 4 papers

Tue 22 Sep· 1 paper

Sun 20 Sep· 1 paper

Sat 19 Sep· 5 papers

Fri 18 Sep· 1 paper

Thu 17 Sep· 3 papers