Autophagosome
Cell component4 papersGO 0005776
- Humans1
- Animals3
Latest
4Dietary restriction activates autophagy through selective oxidation of ATG5
Reversible oxidation of a single cysteine residue enables core autophagosome formation and prevents severe tissue pathology during nutrient limitation…Reversible oxidation of a single cysteine residue enables core autophagosome formation and prevents severe tissue pathology during nutrient limitation in mice.
Dietary CoQ10 ameliorates megakaryocyte dysfunction in aged mice
Male mice treated with CoQ10 for 12 weeks showed enhanced megakaryocyte maturation and polyploidization, accompanied by reduced platelet aggregation…Male mice treated with CoQ10 for 12 weeks showed enhanced megakaryocyte maturation and polyploidization, accompanied by reduced platelet aggregation and activation.
Autophagy flux varies by sex and cell type during human aging
In older adults, higher autophagy flux in blood cells linked to lower physical function and decreased after a 12-week exercise intervention.In older adults, higher autophagy flux in blood cells linked to lower physical function and decreased after a 12-week exercise intervention.
Nuciferine reduces ovariectomy-induced bone loss in rats by activating autophagy
The lotus leaf alkaloid promoted bone formation and osteogenic differentiation in ovariectomized rats through the TFEB autophagy-lysosomal pathway.The lotus leaf alkaloid promoted bone formation and osteogenic differentiation in ovariectomized rats through the TFEB autophagy-lysosomal pathway.