Lysosome
Cell component5 papersMeSH D008247GO 0005764
- Animals3
- Cells1
- In silico1
Latest
5Myelin lipid buildup links to lysosomal defects in mice
Profiling lysosomal fractions from mouse cortex from 3 to 24 months revealed an accumulation of myelin-derived glycosphingolipids that was most…Profiling lysosomal fractions from mouse cortex from 3 to 24 months revealed an accumulation of myelin-derived glycosphingolipids that was most pronounced in microglia.
Lack of dietary DHA drives harmful lipid remodeling and retinal degeneration in mice
Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.
Nuciferine reduces ovariectomy-induced bone loss in rats by activating autophagy
The lotus leaf alkaloid promoted bone formation and osteogenic differentiation in ovariectomized rats through the TFEB autophagy-lysosomal pathway.The lotus leaf alkaloid promoted bone formation and osteogenic differentiation in ovariectomized rats through the TFEB autophagy-lysosomal pathway.