1 paper
Canadian Institutes of Health Research (CIHR) Project GrantCA$1.7mVetenskapsrådetSEK 12.8mJapan Agency for Medical Research and DevelopmentJP¥44.2m
Canadian Institutes of Health Research (CIHR) Project GrantSanté Québec Centre-Sud-de-l’Île-de-Montréal – UniversitaireCA$115k2023–2026
Molecular and cellular mechanisms controlling self-renewal and regeneration of skin
VetenskapsrådetKarolinska InstitutetSEK 4.8m2023–2026
Japan Agency for Medical Research and DevelopmentKyoto UniversityJP¥44.2m2020–2023
The role of O-GlcNAcylation on Notch1 in the self-renewal of muscle satellite cells
Japan Society for the Promotion of ScienceNagoya UniversityJP¥4.3m2019–2021
The role of cellular metabolism in self-renewal and differentiation of stem cells
VetenskapsrådetKarolinska InstitutetSEK 8m2019–2022
Cell division arrest and self-renewal potential of differentiated neurons and heart muscle cells
ZonMwUtrecht University2017–2023
In vivo regulation of stem cell division and self-renewal
Canadian Institutes of Health Research (CIHR) Project GrantInstitute for Research in Immunology and CancerCA$981.2k2017–2022
Canadian Institutes of Health Research (CIHR) Project GrantUniversity of OttawaCA$573.4k2016–2021
In patients under 55, higher levels of a gene-regulating RNA were associated with death, with a reported odds ratio of 6.00.In patients under 55, higher levels of a gene-regulating RNA were associated with death, with a reported odds ratio of 6.00.
Limit: Absolute death risks are not reported, limiting interpretation of the relative odds
Mice carrying one copy of a progeria-linked mutation developed increased gut leakage from 30 weeks, reaching levels reported in naturally aged mice over 20 months old.Mice carrying one copy of a progeria-linked mutation developed increased gut leakage from 30 weeks, reaching levels reported in naturally aged mice over 20 months old.
Limit: The link between mitochondrial dysfunction and impaired cell maturation remains a proposed model
The engineered particles cut friction over 90% compared with commercial hyaluronic acid and reversed chondrocyte senescence in lab models of osteoarthritis.The engineered particles cut friction over 90% compared with commercial hyaluronic acid and reversed chondrocyte senescence in lab models of osteoarthritis.
The method produced 21,500 stem-cell clusters per millilitre of cell-containing printing material for making thymic organoids.The method produced 21,500 stem-cell clusters per millilitre of cell-containing printing material for making thymic organoids.
Researchers found that boosting Lin28b expression during ex vivo culture restores the transplantation and reconstitution capacity of aged mouse hematopoietic stem cells.Researchers found that boosting Lin28b expression during ex vivo culture restores the transplantation and reconstitution capacity of aged mouse hematopoietic stem cells.