Vacuolar atpase inhibitor
1 paper2 findings
- 1 lab in 1 country
- Funders: Agence Nationale de la Recherche and 8 more
- Animals1
Outcomes
2Self-renewal
upin mice1
1 study
Self-renewal
upin mice1
Vacuolar atpase inhibitor improves self-renewal in mice.
“ex vivo lysosomal inhibition boosts old HSCs' in vivo repopulation capacity by over eightfold and improves their self-renewal.”
Animalsex vivo lysosomal inhibition
Reversing lysosomal dysfunction restores youthful state in aged hematopoietic stem cells
Cell stem cell24 Nov 2025
Repopulation capacity
upin mice1
1 study
Repopulation capacity
upin mice1
Vacuolar atpase inhibitor increases repopulation capacity in mice.
“ex vivo lysosomal inhibition boosts old HSCs' in vivo repopulation capacity by over eightfold”
Animalsex vivo lysosomal inhibition
Reversing lysosomal dysfunction restores youthful state in aged hematopoietic stem cells
Cell stem cell24 Nov 2025
Latest
1 in 12 monthsCell Stem Cell
Reversing lysosomal dysfunction restores youthful state in aged hematopoietic stem cells
Experiments in miceBlood and immune system