Myeloid neoplasm

Disease2 papers2 findings

  • Humans2

Associations

2

JAK2

upin humans1

1 study
  1. JAK2 is associated with myeloid neoplasm in humans (6/12 patients).

    Humanssolid tumour NGSn = 12

    Incidental detection of JAK2 V617F mutations in next-generation sequencing analysis of solid tumours: a guide to further workup · Journal of clinical pathology · 1 Oct 2026

JAK2 →

Clonal cytopenia with monocytosis of undetermined significance

upin humans1

1 study
  1. Clonal cytopenia with monocytosis of undetermined significance raises the risk of myeloid neoplasm in humans (13% (7/8 CMML)).

    Humansmedian follow-up of 31 monthsn = 64

    Clinical and molecular characteristics of clonal monocytosis with and without cytopenia(s) · Leukemia · 28 Sep 2026

Clonal cytopenia with monocytosis of undetermined significance →

Latest

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Nature GeneticsHumans

Germline HRD limits therapy-driven clonal hematopoiesis

Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency…Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency reduces this growth.