Repopulation capacity
1 paper
- Animals1
Latest
4 in 12 monthsbioRxiv
Neuropeptide Y deficiency in the bone marrow drives hematopoietic stem and progenitor cell aging
Preprint: experiments in miceBlood and immune system
Nature Communications
Lack of MDA5 delays hematopoietic aging by modulating inflammaging and proteostasis in mice
Experiments in miceProteostasis
bioRxiv
The extent of myeloid skewing in blood is a biomarker of biological aging in mice and humans
Preprint: cohort study in peopleBiomarkers
Cell Stem Cell
Reversing lysosomal dysfunction restores youthful state in aged hematopoietic stem cells
Experiments in miceBlood and immune system
Cell Reports Medicine
Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6-mediated gene editing in hematopoietic stem cells
Experiments in animalsBlood and immune system
Nature Aging
Aberrant engagement of P-selectin drives hematopoietic stem cell aging in mice
Experiments in miceBlood and immune system
The Journal of Experimental Medicine
Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging
Experiments in miceDietary restriction