Galactose

Papers on galactose

414 papers29 new in 30 days

Sunday, November 15

The Journal of Physiology

Exercise and insulin boosted galactose uptake in older men

A randomized crossover trial in eight healthy men averaging 68 years old found that muscles could directly take up galactose, a sugar.A randomized crossover trial in eight healthy men averaging 68 years old found that muscles could directly take up galactose, a sugar.

Figure from The Journal of Physiology
Randomized trial · 8 peopleInsulin

Friday, November 13

Cell Biology and Toxicology

Lowering a protein improved heart relaxation in aged mice

Mice given a heart-cell-targeted gene-silencing injection at 90 weeks had less inflammation and better heart relaxation when assessed at 110 weeks.Mice given a heart-cell-targeted gene-silencing injection at 90 weeks had less inflammation and better heart relaxation when assessed at 110 weeks.

Figure from Cell Biology and Toxicology
Mouse studyMechanisms

Wednesday, November 11

Advanced Science

Valve precursor cells promote age-related scarring in mice

Removing precursor cells reduced valve thickening and scarring in mice given daily D-galactose injections to model aging for about two months.Removing precursor cells reduced valve thickening and scarring in mice given daily D-galactose injections to model aging for about two months.

Figure from Advanced Science
Mouse studyMechanisms

Friday, November 6

Biology

Older female mice lacking a DNA sensor had worse liver injury

An experiment comparing 8- and 56-week-old female mice found the worst damage after interrupted liver blood flow in older mice missing a DNA-sensing enzyme.An experiment comparing 8- and 56-week-old female mice found the worst damage after interrupted liver blood flow in older mice missing a DNA-sensing enzyme.

Damaged liver tissue crowded with inflammatory cells contrasts with orderly tissue, beside a laboratory mouse and a gut lining with gaps.
Mouse studyMechanisms
Phytotherapy Research

6-Shogaol restores bone-forming ability in aged mouse cells

Aged mouse bone marrow stem cells treated for 48 hours in lab experiments broke down more fatty acids and regained the ability to develop into bone-forming cells.Aged mouse bone marrow stem cells treated for 48 hours in lab experiments broke down more fatty acids and regained the ability to develop into bone-forming cells.

Figure from Phytotherapy Research
Animal cell studyBones and joints

Thursday, November 5

Sunday, November 1

Journal of Advanced Research

Plant compound lessened age-related decline in mice

In experiments, ziyu glycoside I reduced functional decline and organ abnormalities in naturally aging mice and mice with chemically induced aging.In experiments, ziyu glycoside I reduced functional decline and organ abnormalities in naturally aging mice and mice with chemically induced aging.

Figure from Journal of Advanced Research
Mouse studyInterventions

Friday, October 30

Thursday, October 29

Scientific Reports

Muscle stem cells reduced organ injury in a mouse aging model

Weekly cell injections improved movement and memory in female KM mice given D-galactose for eight weeks to model accelerated aging.Weekly cell injections improved movement and memory in female KM mice given D-galactose for eight weeks to model accelerated aging.

Liver tissue with intact blue-green cells contrasts with gray tissue full of fat spaces and dark scars, beside a mouse and scattered stem cells.
Mouse studyMuscle

Wednesday, October 28

Tuesday, October 27

Monday, October 26

ESC Congress 2026 Abstract

Progesterone alleviates blood vessel aging in mice

Mice with their ovaries removed that received daily progesterone for six months showed dose-dependent reversals of blood vessel cell aging, inflammation, and impaired…Mice with their ovaries removed that received daily progesterone for six months showed dose-dependent reversals of blood vessel cell aging, inflammation, and impaired relaxation.

Opened arteries beside mice show an orderly dark blue-green lining with sparse inflammatory cells and an irregular gray lining with dense inflammation.
Mouse studyProgesterone
ESC Congress 2026 Abstract

Protein loss made irregular rhythms harder to trigger in mice

Aging mice lacking the protein in heart muscle cells had reduced structural changes in the heart’s upper chambers and lower susceptibility to an experimentally triggered…Aging mice lacking the protein in heart muscle cells had reduced structural changes in the heart’s upper chambers and lower susceptibility to an experimentally triggered irregular heartbeat.

Atrial heart tissue above two mice contrasts extensive scarring and crowded immune cells with more intact fibers and fewer immune cells.
Mouse studyMechanisms

Sunday, October 25

Friday, October 23

Theranostics

Removing a gene reduced age-related bone loss in mice

In experiments with 12 mice per group, deleting the gene in bone-building cells reduced bone loss after 12 weeks of chemically induced aging.In experiments with 12 mice per group, deleting the gene in bone-building cells reduced bone loss after 12 weeks of chemically induced aging.

Osteoblast-specific knockdown of ARG2 alleviates age-related osteoporosis.
Mouse studyBones and joints
Cell Death & Disease

Apelin-13 prevented an aging-related state in lab-grown nerve cells

Experiments in human nerve-cell models found that apelin-13 restored a cellular recycling process disrupted by D-galactose, a sugar used to induce aging-like changes.Experiments in human nerve-cell models found that apelin-13 restored a cellular recycling process disrupted by D-galactose, a sugar used to induce aging-like changes.

APJ system stimulation ameliorated brain aging-related cognitive impairment.
Human cell studyInterventions

Monday, October 19

Friday, October 16