Cardiac fibrosis
Disease2 papers1 finding
- Animals1
Upstream
1Loss of chromosome Y
upin mice1
1 study
Loss of chromosome Y
upin mice1
Loss of chromosome Y induces cardiac fibrosis in mice.
Reviewhematopoietic systemmales
Mosaic Loss of Chromosome Y (LOY): From Genomic Instability to Disease and Single-Cell Detection · Frontiers in bioscience (Landmark edition) · 1 Sep 2026
Latest
2Mosaic Loss of Chromosome Y (LOY): From Genomic Instability to Disease and Single-Cell Detection
ReviewFrontiers in bioscience (Landmark edition)
Lack of the AT2R receptor accelerates cardiac senescence and fibrosis in aging mice
Mice lacking the receptor also showed higher inflammation, elevated DNA damage, and a five-month reduction in median lifespan.
Clinical science (London, England : 1979) · Zacarias-Rodrigues LM et al.