CDKN2A expression

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Interventions

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Tert activator compound

downin human cells1downin mice1

1 study

Tert activator compound decreases CDKN2A expression in mice.
“silences p16INK4a expression via upregulation of DNMT3B-mediated promoter hypermethylation.”
Animalsvia upregulation of DNMT3B-mediated promoter hypermethylation
TERT activation targets DNA methylation and multiple aging hallmarks
Cell21 Jun 2024
Tert activator compound decreases CDKN2A expression in human cells.
“silences p16INK4a expression via upregulation of DNMT3B-mediated promoter hypermethylation.”
Cellsvia upregulation of DNMT3B-mediated promoter hypermethylationprimary human cells
TERT activation targets DNA methylation and multiple aging hallmarks
Cell21 Jun 2024

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