CDKN1A expression
Biomarker1 paper1 finding
- Cells1
Upstream
1TP53
downin cells1
1 study
TP53
downin cells1
TP53 decreases CDKN1A expression in cells.
“Mechanistically, Δ246p53 interacted with FLp53, leading to a decrease in the expression of downstream target genes HDM2 and p21 .”
Cellsinteraction with full-length p53Δ246p53 isoform
New protein form pushed lab-grown cells to stop dividing · Cell death discovery · 7 Oct 2026
Latest
2Cell Death DiscoveryCells
New protein form pushed lab-grown cells to stop dividing
Cell experiments identified a previously unknown protein form that responded to DNA damage and triggered senescence, a state in which cells stop…Cell experiments identified a previously unknown protein form that responded to DNA damage and triggered senescence, a state in which cells stop dividing.