Myofibroma
- Humans1
Effects
1Telomere dysfunction-induced foci
no changein humans1
1 study
Telomere dysfunction-induced foci
no changein humans1
Myofibroma has no effect on telomere dysfunction-induced foci in humans.
“telomere dysfunction-induced foci, measuring telomere-associated DNA damage, showed no notable difference between groups.”
HumansCompared with normal tissuesmyofibroma tissue
Telomere Shortening and p16-Associated Senescence in Myofibromas
Laboratory investigation; a journal of technical methods and pathology29 May 2026
Associations
3Telomere length
downin humans1
1 study
Telomere length
downin humans1
Myofibroma is associated with telomere length in humans.
“Telomere length analysis revealed significantly shorter telomeres in tumors”
HumansCompared with normal tissuesmyofibroma tissue
Telomere Shortening and p16-Associated Senescence in Myofibromas
Laboratory investigation; a journal of technical methods and pathology29 May 2026
53BP1 nuclear foci
upin humans1
1 study
53BP1 nuclear foci
upin humans1
Myofibroma is associated with 53BP1 nuclear foci in humans.
“DNA damage, reflected by an increased number of 53BP1 nuclear foci, was also significantly higher in tumors”
HumansCompared with normal tissuesmyofibroma tissue
Telomere Shortening and p16-Associated Senescence in Myofibromas
Laboratory investigation; a journal of technical methods and pathology29 May 2026
CDKN2A expression
upin humans1
1 study
CDKN2A expression
upin humans1
Myofibroma is associated with CDKN2A expression in humans.
“Tumor tissues exhibited significant p16 overexpression compared with matched normal tissues.”
HumansCompared with matched normal tissuesmyofibroma tissue
Telomere Shortening and p16-Associated Senescence in Myofibromas
Laboratory investigation; a journal of technical methods and pathology29 May 2026