Polyphenols

Polyphenols have no effect on transcriptome in humans.

“Polyphenol supplementation did not meaningfully influence the transcriptional response to exercise training.”

Human trialskeletal muscle12-week

Skeletal Muscle Transcriptomic Responses to Concurrent Training With Polyphenols in Ageing Adults: A Randomized Trial · Journal of cachexia, sarcopenia and muscle · 26 Sep 2026

Polyphenols improve hydration in humans.

“Collagen-based formulations and selected polyphenols demonstrate modest improvements in elasticity, hydration, and wrinkle-related parameters”

Reviewskin

Skin Resilience and Biological Adaptability: Current Clinical Evidence on Micronutrients and Bioactive Compounds · Biomedicines · 18 Sep 2026