Nitrogen dioxide

Intervention4 papers3 findings

  • Humans3

Outcomes

2

Verbal fluency

downin humans1

1 study
  1. Nitrogen dioxide impairs verbal fluency in humans (-0.10 SD, 95% CI -0.19 to 0.00, p = 0.04).

    Humanscomparing 75th percentile with median of NO2 exceedance days14-year decline

    High nitrogen dioxide days linked to faster cognitive decline · medRxiv · 29 Sep 2026 · Preprint

Episodic memory

downin humans1

1 study
  1. Nitrogen dioxide impairs episodic memory in humans (-0.09 SD, 95% CI -0.17 to -0.01, p = 0.02).

    Humanscomparing 75th percentile with median of NO2 exceedance days14-year decline

    High nitrogen dioxide days linked to faster cognitive decline · medRxiv · 29 Sep 2026 · Preprint

Associations

1

Dementia

upin humans1

1 study
  1. Nitrogen dioxide raises the risk of dementia in humans.

    “nitrogen oxides (NO 2 ), and black carbon was associated with increased dementia risk”

    Reviewlong-term

    Environmental Pollution, Biomarkers, and Dementia: An Evidence Review · International journal of molecular sciences · 15 Sep 2026

Dementia →

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medRxivHumansPreprint

High nitrogen dioxide days linked to faster cognitive decline

Comparing the 75th percentile with the median of nitrogen dioxide exceedance days, 14-year decline was -0.09 SD for memory and -0.10 SD for fluency.Comparing the 75th percentile with the median of nitrogen dioxide exceedance days, 14-year decline was -0.09 SD for memory and -0.10 SD for fluency.

Redox BiologyHumans

Proteomics reveals how air pollutants drive chronic disease

In 48,645 UK Biobank participants, plasma proteomic profiles showed shared immune pathways and pollutant-specific mechanisms linking air pollution to…In 48,645 UK Biobank participants, plasma proteomic profiles showed shared immune pathways and pollutant-specific mechanisms linking air pollution to mortality and chronic disease risks.