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No phaseRecruitingGeroscience intervention

Benefits of Nicotinamide Riboside Upon Cognition and Sleep

The Benefits of Nicotinamide Riboside Upon Cognition and Sleep in Older Veterans

Sponsor
State University of New York at Buffalo (Academic or other)
Enrollment
50 planned
Conditions
Cognitive Impairment; Sleep Quality
Interventions
Nicotinamide riboside; Placebo
Ages
older adults
Registry
NCT05500170

Full record on ClinicalTrials.gov

From the registry

Poor sleep quality and short sleep duration may be a mechanistic component of cognitive impairment in older adults, associated with a decline in brain-derived neurotrophic factor. Increasing the availability of nicotinamide adenine dinucleotide (NAD+) with supplementation of its precursor, nicotinamide riboside (NR), a form of vitamin B3 may increase the expression of brain-derived neurotrophic factor. This study proposes to examine the benefits of NR supplementation on sleep and cognitive function in older adults with comprehensive subjective and objective measures and to explore its impacts on serum brain-derived neurotrophic factor.

Primary outcomes

  • Sleep Quality Assessment

History

  1. Primary completion expected

  2. Last registry update

  3. Started

  4. Registered

Papers citing this trial