Myofiber size
downin mice1
Arachidonic acid decreases myofiber size in mice.
“ARA supplementation reduced absolute muscle strength and myofiber size.”
Animalsagingskeletal muscle0.48% w/w12 weeks
bioRxiv : the preprint server for biology10 Jun 2026Preprint
Muscle strength
downin mice1
Arachidonic acid impairs muscle strength in mice.
“ARA supplementation reduced absolute muscle strength and myofiber size.”
Animalsagingskeletal muscle0.48% w/w12 weeks
bioRxiv : the preprint server for biology10 Jun 2026Preprint
Lysosomal activity
upin mice1
Arachidonic acid increases lysosomal activity in mice.
“Further analysis showed that AA delayed ovarian senescence by restoring lysosomal activity in the germ lines of senescent nematodes and mice”
Animalssenescent nematodes and micefemales
Arachidonic Acid Supplementation During Reproductive Aging Prevents Female Fertility Decline
International journal of molecular sciences24 Nov 2025
Ovarian reserve
upin mice1
Arachidonic acid improves ovarian reserve in mice.
“AA supplementation improved the ovarian reserve, increased the oocyte number and quality, and restored fertility.”
Animalsin a mouse model of senescenceovaryfemales
Arachidonic Acid Supplementation During Reproductive Aging Prevents Female Fertility Decline
International journal of molecular sciences24 Nov 2025
Fertility
upin mice1
Arachidonic acid improves fertility in mice.
“In a mouse model of senescence, AA supplementation improved the ovarian reserve, increased the oocyte number and quality, and restored fertility.”
Animalsin a mouse model of senescencefemales
Arachidonic Acid Supplementation During Reproductive Aging Prevents Female Fertility Decline
International journal of molecular sciences24 Nov 2025
Reproductive lifespan
upin worms1
Arachidonic acid improves reproductive lifespan in worms.
“Arachidonic acid (AA) was found to significantly prolong the reproductive lifespan and enhance the quality of senescent oocytes in a cryptic nematode model.”
Model organismsin senescent nematodesfemales
Arachidonic Acid Supplementation During Reproductive Aging Prevents Female Fertility Decline
International journal of molecular sciences24 Nov 2025
Phase 4Results posted1 trial
1 trialPhase 4377 people
The relative rate of new peripheral artery disease was 0.75 for the highest versus lowest fifth of linoleic acid levels.The relative rate of new peripheral artery disease was 0.75 for the highest versus lowest fifth of linoleic acid levels.