LGALS3
Gene1 paper1 findingHGNC 6563MGI 96778NCBI Gene 3958Taxon 9606
- Animals1
Effects
1Retinal degeneration
upin mice1
1 study
Retinal degeneration
upin mice1
LGALS3 increases retinal degeneration in mice.
Animalslater-stage degeneration under prolonged lipid burden; shown by deficiency
Lack of dietary DHA drives harmful lipid remodeling and retinal degeneration in mice · bioRxiv · 28 Sep 2026 · Preprint
Latest
1bioRxivAnimalsPreprint
Lack of dietary DHA drives harmful lipid remodeling and retinal degeneration in mice
Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.