Retinal nerve fiber layer asymmetry

Biomarker1 paper3 findings

  • Humans1

Effects

1

Cardiovascular risk prediction

upin humans1

1 study
  1. Retinal nerve fiber layer asymmetry improves cardiovascular risk prediction in humans.

    Humansn = 46,836

    Intereye retinal asymmetry is linked to cardiovascular risk · Journal of the American Heart Association · 29 Sep 2026

Associations

2

Atrial fibrillation

upin humans1

1 study
  1. Retinal nerve fiber layer asymmetry raises the risk of atrial fibrillation in humans (HR ~1.07 per SD increase).

    Humansn = 46,836

    Intereye retinal asymmetry is linked to cardiovascular risk · Journal of the American Heart Association · 29 Sep 2026

Atrial fibrillation →

Heart failure

upin humans1HR 1.15

1 study
  1. Retinal nerve fiber layer asymmetry raises the risk of heart failure in humans (HR 1.15 per SD increase).

    Humansn = 46,836

    Intereye retinal asymmetry is linked to cardiovascular risk · Journal of the American Heart Association · 29 Sep 2026

Heart failure →

Latest

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Journal of the American Heart AssociationHumans

Intereye retinal asymmetry is linked to cardiovascular risk

In 46,836 adults, each standard deviation increase in retinal nerve fiber layer asymmetry raised heart failure hazard by 1.15 and atrial fibrillation…In 46,836 adults, each standard deviation increase in retinal nerve fiber layer asymmetry raised heart failure hazard by 1.15 and atrial fibrillation hazard by roughly 1.07.