Phosphatidylcholine
Biomarker1 paper3 findings
- Humans1
Associations
3Colorectal cancer
upin silico1
1 study
Colorectal cancer
upin silico1
Colorectal cancer is associated with phosphatidylcholine in silico.
“In the reverse analysis, an increased risk of colorectal cancer was associated with elevated levels of plasma phosphatidylcholine (18:1_18:2).”
In silicoreverse Mendelian randomization analysisplasma
Unveiling the association between plasma lipid species and pan-cancers: A bidirectional 2-sample Mendelian randomization study · Medicine · 1 Sep 2026
Endometrial cancer
upin silico1
1 study
Endometrial cancer
upin silico1
Phosphatidylcholine is associated with endometrial cancer in silico.
“the level of plasma phosphatidylcholine (O-16:0_20:3) was causally linked with endometrial cancer (endometrioid histology)”
In silicoendometrioid histology, forward Mendelian randomization analysisplasma
Unveiling the association between plasma lipid species and pan-cancers: A bidirectional 2-sample Mendelian randomization study · Medicine · 1 Sep 2026
Breast cancer
upin silico1
1 study
Breast cancer
upin silico1
Phosphatidylcholine is associated with breast cancer in silico.
“the level of plasma phosphatidylcholine (O-18:0_16:1) was causally linked with breast cancer (estrogen receptor [ER]+)”
In silicoestrogen receptor [ER]+, forward Mendelian randomization analysisplasma
Unveiling the association between plasma lipid species and pan-cancers: A bidirectional 2-sample Mendelian randomization study · Medicine · 1 Sep 2026
Latest
5Loss of the lipid enzyme PNPLA7 impairs skeletal muscle and mitochondria in mice
Researchers identified PNPLA7 as an essential regulator of phosphatidylcholine catabolism necessary for maintaining mouse muscle fiber size and…Researchers identified PNPLA7 as an essential regulator of phosphatidylcholine catabolism necessary for maintaining mouse muscle fiber size and endurance.
Mild caloric restriction accelerates atherosclerosis in mice
In ApoE-deficient mice fed for six months, mild food restriction reduced weight gain by 5% but increased circulating cholesterol and accelerated…In ApoE-deficient mice fed for six months, mild food restriction reduced weight gain by 5% but increased circulating cholesterol and accelerated plaque formation.
Plasma metabolic shifts link to T-cell senescence and mortality in older COVID-19 patients
Dysregulated phospholipid and bile acid metabolism tracked with cytokine spikes and 180-day mortality, while a specific lipid attenuated senescent…Dysregulated phospholipid and bile acid metabolism tracked with cytokine spikes and 180-day mortality, while a specific lipid attenuated senescent markers in cell tests.