Phosphatidylethanolamine
Biomarker2 papers2 findings
- Humans1
- Model organisms1
Upstream
1psd-1
downin worms1−70%
1 study
psd-1
downin worms1−70%
psd-1 decreases phosphatidylethanolamine in worms (-69.51%).
“mitochondrial PE levels were reduced by 69.51% in psd-1 knockdown worms compared to controls”
Model organismscompared to controls
Suppressing clk-1 restores lifespan and mitochondrial function in psd-1 deficient worms · Antioxidants (Basel, Switzerland) · 20 Sep 2026
Associations
1Pancreatic cancer
upin silico1
1 study
Pancreatic cancer
upin silico1
Phosphatidylethanolamine is associated with pancreatic cancer in silico.
“the level of plasma phosphatidylethanolamine (18:0_20:4) was causally linked with pancreatic cancer”
In silicoin forward Mendelian randomization analysisplasma
Unveiling the association between plasma lipid species and pan-cancers: A bidirectional 2-sample Mendelian randomization study · Medicine · 1 Sep 2026
Latest
5HDL particle sizes show contrasting links to dementia risk
In 23,790 older adults, higher small HDL levels tracked lower dementia risk (hazard ratios 0.89 to 0.91), while very large HDL tracked higher risk…In 23,790 older adults, higher small HDL levels tracked lower dementia risk (hazard ratios 0.89 to 0.91), while very large HDL tracked higher risk (1.10 to 1.14).
Mild caloric restriction accelerates atherosclerosis in mice
In ApoE-deficient mice fed for six months, mild food restriction reduced weight gain by 5% but increased circulating cholesterol and accelerated…In ApoE-deficient mice fed for six months, mild food restriction reduced weight gain by 5% but increased circulating cholesterol and accelerated plaque formation.
Plasma metabolic shifts link to T-cell senescence and mortality in older COVID-19 patients
Dysregulated phospholipid and bile acid metabolism tracked with cytokine spikes and 180-day mortality, while a specific lipid attenuated senescent…Dysregulated phospholipid and bile acid metabolism tracked with cytokine spikes and 180-day mortality, while a specific lipid attenuated senescent markers in cell tests.
Suppressing clk-1 restores lifespan and mitochondrial function in psd-1 deficient worms
Targeting ubiquinone biosynthesis counteracted reduced oxygen consumption and rescued lifespan loss caused by mitochondrial phosphatidylethanolamine…Targeting ubiquinone biosynthesis counteracted reduced oxygen consumption and rescued lifespan loss caused by mitochondrial phosphatidylethanolamine deficiency in Caenorhabditis elegans.