Neuromuscular junctions

Biomarker

1 paper

  • Animals1

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RAS/MAPK overactivation drives motor axon loss in flies

An unbiased genetic screen in Drosophila revealed that excessive RAS/MAPK signaling causes adult-onset neurodegeneration that a MEK inhibitor rescues in a dose-dependent…An unbiased genetic screen in Drosophila revealed that excessive RAS/MAPK signaling causes adult-onset neurodegeneration that a MEK inhibitor rescues in a dose-dependent manner.

Experiments in fliesMAPK/ERK signalling
European Journal of Applied Physiology

Ramadan fasting is linked to respiratory sarcopenia in older men

In 53 older men and 48 older women, 28 days of fasting lowered maximal expiratory pressure in men while shifting plasma neuromuscular markers in both sexes.In 53 older men and 48 older women, 28 days of fasting lowered maximal expiratory pressure in men while shifting plasma neuromuscular markers in both sexes.

Study in peopleLung