Autophagic flux

Biomarker

5 papers

  • Animals4

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Aging Cell

Ginseng compound extended lifespan and preserved movement in worms

In worm experiments, the ginseng-derived compound also preserved touch sensitivity and restored age-impaired function in nerve cells’ waste-processing compartments.In worm experiments, the ginseng-derived compound also preserved touch sensitivity and restored age-impaired function in nerve cells’ waste-processing compartments.

Experiments in wormsInterventions
Nature Communications

Targeting a cell regulator reduced bone loss in mice

In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.

Experiments in miceBones and joints
Aging Cell

Dietary CoQ10 ameliorates megakaryocyte dysfunction in aged mice

Male mice treated with CoQ10 for 12 weeks showed enhanced megakaryocyte maturation and polyploidization, accompanied by reduced platelet aggregation and activation.Male mice treated with CoQ10 for 12 weeks showed enhanced megakaryocyte maturation and polyploidization, accompanied by reduced platelet aggregation and activation.

Experiments in miceInterventions
Advanced Science

Alternate-day fasting curbs liver fibrosis in mice

In mouse models, alternate-day fasting stimulated hepatocyte nitric oxide production to suppress stellate cell activation, an effect abolished by hepatocyte eNOS…In mouse models, alternate-day fasting stimulated hepatocyte nitric oxide production to suppress stellate cell activation, an effect abolished by hepatocyte eNOS deletion.

Experiments in miceLiver fibrosis