TO expression

Biomarker

1 paper1 finding

  • Model organisms1

Interventions

1

Queen removal

upin S. invicta1

1 study
  1. Queen removal increases TO expression in S. invicta.

    “The queen's absence mildly affects gene expression in major workers, but TO and MRJP1 expression rise in minors.”

    Model organismsminor workers after queen removal

    Multi-Omics Analysis Reveals TO Gene's Association With Food Selection and Lifespan in Minor-Worker Ants Post-Queen Loss

    Ecology and evolution7 Jun 2025

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bioRxiv

Progeria disrupts cells in the intestinal lining in mice

Mice carrying one copy of a progeria-linked mutation developed increased gut leakage from 30 weeks, reaching levels reported in naturally aged mice over 20 months old.Mice carrying one copy of a progeria-linked mutation developed increased gut leakage from 30 weeks, reaching levels reported in naturally aged mice over 20 months old.

Preprint: experiments in miceLMNA
Journal of Neuroinflammation

Protein loss promotes age-linked brain cell activation in mice

In experiments, aged mice lacking the protein showed stronger age-linked brain cell activation, but no obvious loss of nerve insulation or faster decline in movement.In experiments, aged mice lacking the protein showed stronger age-linked brain cell activation, but no obvious loss of nerve insulation or faster decline in movement.

Experiments in miceMechanisms
NPJ Aging

Lactate worsened arthritis and bone erosion in animals

In animals with induced arthritis, blocking lactate transport reduced disease progression more effectively than blocking the body's own lactate production.In animals with induced arthritis, blocking lactate transport reduced disease progression more effectively than blocking the body's own lactate production.

Experiments in animalsBones and joints