Mitophagy markers

4 papers

Human trial1
Animals3

Latest

5 in 12 months

iScience13 Oct

Topical application of urolithin A activates mitophagy and enhances mitochondrial function to promote skin longevity

Randomised trial in peopleUrolithin A

Translational Vision Science & Technology18 Jun

Therapeutic Potential of miR-196a in Protecting Corneal Endothelial Cells From Senescence Through Mitochondrial and TGF-β Signaling Modulation

Experiments in human cellsTGF-β signalling

Aging Cell16 Apr

Ghrelin Receptor Deletion or Pharmacological Inhibition Improves Muscle Function in Aging Male Mice

Experiments in miceMuscle

npj Aging6 Mar

Early mitophagy activation by Urolithin A prevents, but late activation does not reverse, age-related cognitive impairment

Experiments in miceUrolithin A

Biochimica et Biophysica Acta General Subjects19 Dec

Spermidine deficiency induces BNIP3/LC3B-mediated mitophagy in the salivary glands of accelerated aging mice

Experiments in animalsSpermidine

International Journal of Surgery1 Jul

Targeting SIRT3 to regulate mitophagy-dependent ferroptosis for preventing glucocorticoid-induced osteoporosis

Experiments in ratsFerroptosis

GeroScience1 Jul

Adaptations of mitochondrial, autophagy and nutrient sensing pathways in the liver from long-lived mice overexpressing CYB5R3 are sex-dependent and involve inter-organ responses

Experiments in miceNutrient sensing

PNAS18 Jun

Tumor-promoting UBR4 coordinates impaired mitophagy-associated senescence and lung adenocarcinoma pathogenesis

Experiments in miceMitophagy

Life Sciences22 Feb

Alda-1 mediates cell senescence and counteracts bone loss in weightlessness through regulating mitophagy

Experiments in ratsBone loss

Aging21 Apr

Aberrant expression of thyroidal hormone receptor α exasperating mitochondrial dysfunction induced sarcopenia in aged mice

Experiments in animalsMechanisms