2 papers1 finding
Cancer
upin reviews1
Cancer is associated with membrane potential (Membrane depolarization from -70mV to -15mV).
“Cancer as Axial Collapse: Formalized as a transition from organized rotational movement to disordered translational dispersal, measurable via membrane depolarization (from -70mV to -15mV) and mitochondrial cristae loss.”
ReviewProposed theoretical framework
Zenodo (CERN European Organization for Nuclear Research)22 Mar 2026Preprint
Japan Society for the Promotion of ScienceJP¥6.4mSwiss National Science Foundation
In an animal experiment, drug-carrying particles preserved bone structure and enhanced bone formation in mice whose ovaries had been removed.In an animal experiment, drug-carrying particles preserved bone structure and enhanced bone formation in mice whose ovaries had been removed.
In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.
In mice lacking ovaries to mimic estrogen loss, deleting the Camkk1 gene from bone-degrading cells attenuated the loss of spongy bone.In mice lacking ovaries to mimic estrogen loss, deleting the Camkk1 gene from bone-degrading cells attenuated the loss of spongy bone.
In an osteoporosis animal model, mitochondria from treated stem cells promoted blood vessel formation and restored the structure of spongy bone.In an osteoporosis animal model, mitochondria from treated stem cells promoted blood vessel formation and restored the structure of spongy bone.
In ApoE-/- mice, rapamycin reduced aortic lipid-positive area from 25.32 ± 0.98% to 12.28 ± 1.49% and increased plaque efferocytosis index from 0.36 ± 0.02 to 1.37 ±…In ApoE-/- mice, rapamycin reduced aortic lipid-positive area from 25.32 ± 0.98% to 12.28 ± 1.49% and increased plaque efferocytosis index from 0.36 ± 0.02 to 1.37 ± 0.15.
A screen of 800 natural compounds identified a phytochemical that activates autophagy and restores cell-cycle activity in models of cellular exhaustion.A screen of 800 natural compounds identified a phytochemical that activates autophagy and restores cell-cycle activity in models of cellular exhaustion.